Kyogashima M
Seikagaku Corporation Tokyo Research Institute, 1253, Tateno 3-chome Higashiyamato-shi, Tokyo 207-0021, Japan.
Adv Exp Med Biol. 2001;491:343-50. doi: 10.1007/978-1-4615-1267-7_22.
It has long been controversial whether sulfatide stimulates blood coagulation or inhibits blood coagulation. In this paper, I demonstrated not only anticoagulant activity but also coagulant activity of sulfatide in vivo by using experimental animal models and presented the possibility that sulfatide may function contradictorily under physiological and/or pathological conditions. For instance, I presented possible involvement of sulfatide in thrombotic diseases associated with cancers.
