Smith S
Department of Obstetrics and Gynecology, Sinai Hospital of Baltimore, Maryland 21215.
J Reprod Med. 1992 Sep;37(9):785-8.
Recent data suggest that endometrial maturation correlates highly with the postovulatory day as determined by ultrasound or identification of the urinary luteinizing hormone (LH) surge. A study was performed to determine the level of correlation between two methods of endometrial biopsy (EB) interpretation. Method 1 correlated histology with the onset of the next menstrual period; method 2 correlated it with the postovulatory day relative to the LH surge. Forty EBs were analyzed. Both methods agreed that 20/40 EBs were in phase and 6/40 EBs were out of phase (greater than a two-day lag between histologic endometrial maturation and chronologic dating). Of the remaining 14 EBs, 8 were in phase by method 1 and out of phase by method 2, and 6 were out of phase by method 1 and in phase by method 2. Thus, 35% of EBs were considered in phase by one method and out of phase by the alternative method. This implies that 35% of management decisions regarding whether to repeat an EB or treat an out-of-phase EB may be influenced by the method of interpreting EBs.
近期数据表明，经超声检查或检测尿促黄体生成素（LH）峰确定，子宫内膜成熟度与排卵后天数高度相关。开展了一项研究，以确定两种子宫内膜活检（EB）解读方法之间的相关程度。方法1将组织学结果与下一次月经来潮时间相关联；方法2将其与相对于LH峰的排卵后天数相关联。分析了40例EB。两种方法均认为，40例EB中有20例处于同步期，6例不同步（组织学子宫内膜成熟度与按时间顺序推算的日期之间相差超过两天）。在其余14例EB中，8例按方法1处于同步期，按方法2不同步，6例按方法1不同步，按方法2处于同步期。因此，35%的EB按一种方法被视为同步期，按另一种方法则被视为不同步。这意味着，在决定是否重复进行EB或治疗不同步EB时，35%的管理决策可能会受到EB解读方法的影响。
