前列腺癌患者多民族队列中的诊断分期与生存率
Stage at diagnosis and survival in a multiethnic cohort of prostate cancer patients.
作者信息
Oakley-Girvan Ingrid, Kolonel Laurence N, Gallagher Richard P, Wu Anna H, Felberg Anna, Whittemore Alice S
机构信息
Stanford University School of Medicine, Stanford, California 94305-5405, USA.
出版信息
Am J Public Health. 2003 Oct;93(10):1753-9. doi: 10.2105/ajph.93.10.1753.
Abstract
OBJECTIVES
We evaluated the effects of socioeconomic status and comorbidity on stage of disease and survival among 1509 population-based prostate cancer patients.
METHODS
We applied logistic regression and Cox proportional hazards regression to data from Whites, African Americans, and Asian Americans who were diagnosed from 1987 to 1991.
RESULTS
Patients with existing comorbid conditions were less likely than those without these conditions to be diagnosed with advanced cancer. Compared with Whites, African Americans (odds ratio [OR] = 1.5; 95% confidence interval [CI] = 1.1, 2.2) and foreign-born Asian Americans (OR = 1.6; 95% CI = 1.0, 2.4) were more likely to be diagnosed with advanced cancer. Among men with localized disease, prostate cancer death rates were higher for African Americans than for Whites (death rate ratio = 2.3; 95% CI = 1.2, 4.7).
CONCLUSIONS
These findings support the need for further investigation of factors that affect access to and use of health care among African Americans and Asian Americans.
摘要
目的
我们评估了社会经济地位和合并症对1509名基于人群的前列腺癌患者的疾病分期和生存情况的影响。
方法
我们对1987年至1991年期间诊断出的白人、非裔美国人和亚裔美国人的数据应用了逻辑回归和Cox比例风险回归。
结果
患有合并症的患者比没有这些合并症的患者被诊断为晚期癌症的可能性更小。与白人相比，非裔美国人（优势比[OR]=1.5；95%置信区间[CI]=1.1,2.2）和出生在国外的亚裔美国人（OR=1.6；95%CI=1.0,2.4）被诊断为晚期癌症的可能性更大。在患有局限性疾病的男性中，非裔美国人的前列腺癌死亡率高于白人（死亡率比=2.3；95%CI=1.2,4.7）。
结论
这些发现支持需要进一步调查影响非裔美国人和亚裔美国人获得和使用医疗保健的因素。
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本文引用的文献
1
THE PRE-THERAPEUTIC CLASSIFICATION OF CO-MORBIDITY IN CHRONIC DISEASE.慢性病共病的治疗前分类
J Chronic Dis. 1970 Dec;23(7):455-68. doi: 10.1016/0021-9681(70)90054-8.
2
Choosing area based socioeconomic measures to monitor social inequalities in low birth weight and childhood lead poisoning: The Public Health Disparities Geocoding Project (US).选择基于区域的社会经济指标来监测低出生体重和儿童铅中毒方面的社会不平等现象：公共卫生差异地理编码项目（美国）
J Epidemiol Community Health. 2003 Mar;57(3):186-99. doi: 10.1136/jech.57.3.186.
3
Cancer statistics, 2003.2003年癌症统计数据。
CA Cancer J Clin. 2003 Jan-Feb;53(1):5-26. doi: 10.3322/canjclin.53.1.5.
4
Geocoding and monitoring of US socioeconomic inequalities in mortality and cancer incidence: does the choice of area-based measure and geographic level matter?: the Public Health Disparities Geocoding Project.美国死亡率和癌症发病率的社会经济不平等的地理编码与监测：基于区域的测量方法和地理层级的选择是否重要？：公共卫生差异地理编码项目
Am J Epidemiol. 2002 Sep 1;156(5):471-82. doi: 10.1093/aje/kwf068.
5
Effect of patient socioeconomic status on physician profiles for prevention, disease management, and diagnostic testing costs.患者社会经济状况对医生在预防、疾病管理及诊断检测成本方面表现的影响。
Med Care. 2002 Aug;40(8):717-24. doi: 10.1097/00005650-200208000-00011.
6
7
Socioeconomic disparities in health: pathways and policies.健康方面的社会经济差异：途径与政策
Health Aff (Millwood). 2002 Mar-Apr;21(2):60-76. doi: 10.1377/hlthaff.21.2.60.
8
9
Changing relationship between socioeconomic status and prostate cancer incidence.社会经济地位与前列腺癌发病率之间不断变化的关系。
J Natl Cancer Inst. 2001 May 2;93(9):705-9. doi: 10.1093/jnci/93.9.705.
10
Socioeconomic status, ethnicity, and health care access among young and healthy women.年轻健康女性的社会经济地位、种族和医疗保健可及性
Ethn Dis. 2001 Winter;11(1):60-71.
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