阿德勒灵长类动物中心猕猴的淀粉样变性
Amyloidosis in macaques in adler primatological center.
作者信息
Naumenko E S, Krylova R I
机构信息
Institute of Medical Primatology, Russian Academy of Medical Sciences, Sochi-Adler.
出版信息
Bull Exp Biol Med. 2003 Jul;136(1):80-3. doi: 10.1023/a:1026005416942.
Results of pathomorphological studies of 133 amyloidosis cases in macaques of 3 species (M. mulatta, M. nemestrina, and M. fascicularis) in the Adler Primatological Center are presented. A relationship between the development of amyloidosis and animal age is detected and the incidence of involvement of various organs is determined. Generalized and isolated forms of amyloidosis are described, the most incident of which (36.8%) was hepatic amyloidosis. Simian and human amyloidosis are compared. Amyloidosis in macaques can be used as the model process for studies of amyloidosis in humans.
本文展示了阿德勒灵长类动物中心对3种猕猴（恒河猴、豚尾猴和食蟹猴）的133例淀粉样变性病例进行病理形态学研究的结果。检测了淀粉样变性的发展与动物年龄之间的关系，并确定了各器官受累的发生率。描述了全身性和局限性淀粉样变性形式，其中最常见的（36.8%）是肝淀粉样变性。对猿类和人类淀粉样变性进行了比较。猕猴的淀粉样变性可作为研究人类淀粉样变性的模型过程。
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