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中国汕头逐步淘汰含铅汽油后儿童的血铅水平。

Children's blood lead levels after the phasing out of leaded gasoline in Shantou, China.

作者信息

Luo Wenhong, Zhang Yuan, Li Hui

机构信息

The Central Laboratory, Shantou University Medical College, Shantou, Guangdong, People's Republic of China.

出版信息

Arch Environ Health. 2003 Mar;58(3):184-7. doi: 10.3200/AEOH.58.3.184-187.

Abstract

Shantou, a city in the People's Republic of China, has a central urban population of approximately 700,000 and a large number of registered vehicles (motorcycles = 256,600; other motor vehicles = 261,000). Shantou is designated as 1 of the 5 Special Economic Zones in China. The use of leaded gasoline was prohibited in the city at the end of 1998. Blood samples for lead analysis were collected from children aged 1-5 yr during the summers of 1999-2001, and the samples were analyzed using graphite furnace atomic absorption spectrometry. In 1999, 44.3% (147/332) of the children had mean blood lead levels in excess of 100 microg/l. The percentage of children with blood lead levels that exceeded 100 microg/l was reduced to 35.8% (227/635) and 23.0% (105/457) in 2000 and 2001, respectively. Average blood lead levels declined from 104 microg/l, to 94 microg/l, and 79 microg/l during the 3-yr period, respectively; the respective concordant geometric means were 97 microg/l, 85 microg/l, and 71 microg/l. Mean blood lead levels for the children studied decreased significantly (p < 0.05) every year. Among all children tested during the 3-yr period, there were no significant differences by gender and no significant differences between children who were between the ages of 2 and 3 yr; however, those who were 4 yr of age had blood lead levels that were significantly (p < 0.05) higher than levels in those 2 and 3 yr of age.

摘要

中国汕头市的中心城区人口约70万,登记车辆众多(摩托车 = 256,600辆;其他机动车 = 261,000辆)。汕头是中国5个经济特区之一。1998年底该城市禁止使用含铅汽油。于1999 - 2001年夏季采集1 - 5岁儿童的血样用于铅分析,并采用石墨炉原子吸收光谱法进行检测。1999年,44.3%(147/332)的儿童平均血铅水平超过100μg/l。血铅水平超过100μg/l的儿童比例在2000年降至35.8%(227/635),2001年降至23.0%(105/457)。在这3年期间,平均血铅水平分别从104μg/l降至94μg/l和79μg/l;相应的几何均值分别为97μg/l、85μg/l和71μg/l。所研究儿童的平均血铅水平每年均显著下降(p < 0.05)。在这3年期间接受检测的所有儿童中,性别间无显著差异,2至3岁儿童之间也无显著差异;然而,4岁儿童的血铅水平显著高于(p < 0.05)2岁和3岁儿童。

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