Gehanno P, Guedon C, Barry B, Depondt J, Kebaili C
Department of Head and Neck Surgery, University Hospital Bichat-Claude Bernard, Paris.
Laryngoscope. 1992 Dec;102(12 Pt 1):1369-71. doi: 10.1288/00005537-199212000-00011.
Opinions are divided over the validity of total glossectomy without associated total laryngectomy for advanced carcinoma of the tongue. This retrospective study evaluates the oncologic and functional results obtained in 80 patients who underwent total glossectomy as a primary procedure or as salvage surgery. Satisfactory swallowing ability was obtained in 41 patients, and speech was understandable in 49 patients. The survival rate at 1 year was 65%, with early recurrence of the disease, which was especially frequent in patients with prior radiotherapy, being the major cause of death. The study confirms the poor prognosis of cases with mandibular involvement, and the fact that partial laryngectomy, when required, impairs functional results. In the light of the authors' experience, total glossectomy without total laryngectomy should only be undertaken in motivated and well-supported patients able to accomplish the difficult rehabilitation process.
对于晚期舌癌患者,在不进行全喉切除术的情况下实施全舌切除术的有效性,各方观点存在分歧。本回顾性研究评估了80例接受全舌切除术作为主要手术或挽救性手术患者的肿瘤学和功能结果。41例患者获得了满意的吞咽能力,49例患者的言语可被理解。1年生存率为65%,疾病早期复发是主要死亡原因,在接受过放疗的患者中尤为常见。该研究证实了下颌骨受累病例预后较差,以及在需要时进行部分喉切除术会损害功能结果这一事实。根据作者的经验,不进行全喉切除术的全舌切除术仅应在有积极性且得到充分支持、能够完成艰难康复过程的患者中进行。