Quigley M R, Shih T, Elrifai A, Maroon J C, Lesiecki M L
Allegheny General Hospital, Pittsburgh, Pennsylvania 15212.
Lasers Surg Med. 1992;12(6):621-4. doi: 10.1002/lsm.1900120609.
A prototype Ho:YAG (2.15 microns) laser operating at 2-J/pulse, 3 Hz through a 600-microns fiber was employed to perform laser discectomies at the L3-4 disc through an 18G needle in five juvenile pigs. No temperature elevations were recorded in the posterior longitudinal ligament at the disc level and all animals recovered fully with no adverse sequelae, even immediately upon awakening from anesthesia. Pathologic examination demonstrated a wide swath of coagulation necrosis confined to the disc space. The Ho:YAG laser, owing to its close approximation to the intense 2.0 microns absorption band of water, appears to be a viable candidate for clinical trials of laser discectomy.
使用一台 Ho:YAG（2.15 微米）原型激光，以 2 焦耳/脉冲、3 赫兹的频率通过一根 600 微米的光纤，经 18G 针头对五只幼年猪的 L3 - 4 椎间盘进行激光椎间盘切除术。在椎间盘水平的后纵韧带处未记录到温度升高，所有动物均完全康复，无不良后遗症，甚至在麻醉苏醒后即刻也是如此。病理检查显示大片凝固性坏死局限于椎间盘间隙。Ho:YAG 激光由于其接近水的强烈 2.0 微米吸收带，似乎是激光椎间盘切除术临床试验的一个可行候选者。
