Nerubay J, Caspi I, Levinkopf M, Tadmor A, Bubis J J
Spinal Deformities Unit, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Clin Orthop Relat Res. 1997 Apr(337):42-4. doi: 10.1097/00003086-199704000-00005.
Percutaneous laser discectomy has developed as a new modality in the treatment of herniated intervertebral discs. An experimental study of percutaneous nucleolysis using a carbon dioxide laser beam was performed in 10 dogs, each dog having 2 intervertebral disc spaces treated, for a total of 20 discs. The intradiscal pressure decreased in all instances with the drop ranging from 10% to 55% at the L2-L3 disc and 40% to 69% at the L4-L5 disc. The macroscopic and microscopic studies showed vaporization of the nucleus pulposus, and in 8 spaces, thermal damage to the end plate was observed. This study suggests that carbon dioxide laser nucleolysis is easy and effective, but 300 J of laser energy can damage the end plates in some intervertebral discs in dogs.
经皮激光椎间盘切除术已发展成为治疗椎间盘突出症的一种新方法。对10只狗进行了一项使用二氧化碳激光束进行经皮髓核溶解的实验研究，每只狗有2个椎间盘间隙接受治疗，总共20个椎间盘。所有情况下椎间盘内压力均下降，L2-L3椎间盘压力下降幅度为10%至55%，L4-L5椎间盘压力下降幅度为40%至69%。宏观和微观研究显示髓核汽化，在8个间隙中观察到终板热损伤。这项研究表明，二氧化碳激光髓核溶解术简便有效，但300焦耳的激光能量可在某些犬椎间盘内损伤终板。
