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职业性接触氯工人的免疫状况

[Immunological profile of workers occupationally exposed to chlorine].

作者信息

Moszczyński P, Słowiński S

机构信息

Wojewódzkiej Pracowni Immunologicznej Zespołu Opieki Zdrowotnej, Brzesku.

出版信息

Med Pr. 1992;43(4):303-8.

PMID:1453946
Abstract

Immunological profile of 42 men working under exposure to chlorine for a period from 2 to 38 years was analysed. Toxicological analyses of air samples which were carried out for 20 years showed similar chlorine concentration ranging from 0.21 to 1.05 mg/m3. The number of B, T, and non-B, non-T lymphocytes was determined as well as the C3c, C4 complement components and proteins of acute phase reaction: alpha 1-acid-glycoprotein, haptoglobin and ceruloplasmin in the serum. Chronic exposure to chlorine produced a stimulating effect on the immune system, which was manifested by elevated IgA, IgD and IgM levels, the concentration of acute phase reaction proteins and increased number of B lymphocytes. The observed phenomenon had no influence on the antibacterial and anticancer immunity of the workers.

摘要

对42名在氯气环境中工作2至38年的男性的免疫状况进行了分析。20年期间对空气样本进行的毒理学分析显示,氯浓度相似,范围为0.21至1.05毫克/立方米。测定了血清中B、T和非B、非T淋巴细胞的数量以及C3c、C4补体成分和急性期反应蛋白:α1-酸性糖蛋白、触珠蛋白和铜蓝蛋白。长期接触氯气对免疫系统产生了刺激作用,表现为IgA、IgD和IgM水平升高、急性期反应蛋白浓度增加以及B淋巴细胞数量增多。观察到的这种现象对工人的抗菌和抗癌免疫力没有影响。

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