Nepom G T, Nepom B S
Immunology Program, Virginia Mason Research Center, Seattle, Washington.
Rheum Dis Clin North Am. 1992 Nov;18(4):785-92.
Recent methodologic advances now allow the precise identification of HLA genes in individuals. Population studies using these methods have pinpointed the HLA alleles strongly associated with rheumatoid arthritis (RA). This article summarizes the current status of these RA-associated HLA genes in disease susceptibility and uses that information to derive estimates of risk ratios for prediction of disease in an individual.
