阿尔茨海默病中的活化小胶质细胞和脑淀粉样沉积物 - Suppr

Suppr

超能文献

Activated microglia and cerebral amyloid deposits in Alzheimer's disease.

作者信息

Rozemuller J M, van der Valk P, Eikelenboom P

机构信息

Dept of Psychiatry, Institute of Pathology, Amsterdam.

出版信息

Res Immunol. 1992 Jul-Aug;143(6):646-9. doi: 10.1016/0923-2494(92)80050-u.

DOI:10.1016/0923-2494(92)80050-u

PMID:1455057

Abstract

摘要

相似文献

Activated microglia and cerebral amyloid deposits in Alzheimer's disease.阿尔茨海默病中的活化小胶质细胞和脑淀粉样沉积物

Res Immunol. 1992 Jul-Aug;143(6):646-9. doi: 10.1016/0923-2494(92)80050-u.

T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer's disease-like cerebral amyloidosis.阿尔茨海默病样脑淀粉样变性转基因模型中的 T 细胞脑浸润和未成熟抗原呈递细胞。

Brain Behav Immun. 2016 May;54:211-225. doi: 10.1016/j.bbi.2016.02.009. Epub 2016 Feb 9.

Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease.在阿尔茨海默病动物模型中，炎症与脑淀粉样变性无关联。

J Neuroimmunol. 2003 Apr;137(1-2):32-41. doi: 10.1016/s0165-5728(03)00037-7.

Brain amyloid in normal aging and cerebral amyloid angiopathy is antigenically related to Alzheimer's disease beta-protein.正常衰老和脑淀粉样血管病中的脑淀粉样蛋白在抗原性上与阿尔茨海默病β蛋白相关。

Am J Pathol. 1987 Dec;129(3):422-8.

Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain.

J Neuroimmunol. 2002 Oct;131(1-2):135-46. doi: 10.1016/s0165-5728(02)00272-2.

On the Role of Platelet-Generated Amyloid Beta Peptides in Certain Amyloidosis Health Complications.血小板生成的β淀粉样肽在某些淀粉样变性并发症中的作用。

Front Immunol. 2020 Oct 2;11:571083. doi: 10.3389/fimmu.2020.571083. eCollection 2020.

Peripheral Tumor Necrosis Factor-Alpha (TNF-α) Modulates Amyloid Pathology by Regulating Blood-Derived Immune Cells and Glial Response in the Brain of AD/TNF Transgenic Mice.外周肿瘤坏死因子-α（TNF-α）通过调节AD/TNF转基因小鼠大脑中源自血液的免疫细胞和神经胶质反应来调节淀粉样蛋白病理学。

J Neurosci. 2017 May 17;37(20):5155-5171. doi: 10.1523/JNEUROSCI.2484-16.2017. Epub 2017 Apr 25.

Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1.白细胞介素-1可诱导人星形胶质细胞中阿尔茨海默病淀粉样蛋白促进因子抗胰凝乳蛋白酶的表达。

Neuron. 1995 Feb;14(2):447-56. doi: 10.1016/0896-6273(95)90300-3.

Microglia and Alzheimer's disease.小胶质细胞与阿尔茨海默病

Curr Opin Hematol. 1999 Jan;6(1):15-24. doi: 10.1097/00062752-199901000-00004.

Molecular pathogenesis of beta-amyloidosis in Alzheimer's disease and other cerebral amyloidoses.

Lab Invest. 1995 Jan;72(1):4-16.

引用本文的文献

Post-symptomatic NLRP3 inhibition rescues cognitive impairment and mitigates amyloid and tau driven neurodegeneration.症状出现后抑制NLRP3可挽救认知障碍，并减轻淀粉样蛋白和tau蛋白驱动的神经退行性变。

NPJ Dement. 2025;1(1):3. doi: 10.1038/s44400-025-00011-5. Epub 2025 May 6.

Microglia and Cholesterol Handling: Implications for Alzheimer's Disease.小胶质细胞与胆固醇代谢：对阿尔茨海默病的影响

Biomedicines. 2022 Dec 1;10(12):3105. doi: 10.3390/biomedicines10123105.

Possible Neuropathology of Sleep Disturbance Linking to Alzheimer's Disease: Astrocytic and Microglial Roles.与阿尔茨海默病相关的睡眠障碍的可能神经病理学：星形胶质细胞和小胶质细胞的作用。

Front Cell Neurosci. 2022 Jun 9;16:875138. doi: 10.3389/fncel.2022.875138. eCollection 2022.

Formulated Chinese medicine Shaoyao Gancao Tang reduces NLRP1 and NLRP3 in Alzheimer's disease cell and mouse models for neuroprotection and cognitive improvement.中药芍药甘草汤通过减少阿尔茨海默病细胞和小鼠模型中的 NLRP1 和 NLRP3 实现神经保护和认知改善。

Aging (Albany NY). 2021 Jun 9;13(11):15620-15637. doi: 10.18632/aging.203125.

Cell-Type-Specific Gene Modules Related to the Regional Homogeneity of Spontaneous Brain Activity and Their Associations With Common Brain Disorders.与自发脑活动区域同质性相关的细胞类型特异性基因模块及其与常见脑部疾病的关联。

Front Neurosci. 2021 Apr 20;15:639527. doi: 10.3389/fnins.2021.639527. eCollection 2021.

Chronic stress as a risk factor for Alzheimer's disease: Roles of microglia-mediated synaptic remodeling, inflammation, and oxidative stress.慢性应激作为阿尔茨海默病的一个风险因素：小胶质细胞介导的突触重塑、炎症和氧化应激的作用。

Neurobiol Stress. 2018 May 19;9:9-21. doi: 10.1016/j.ynstr.2018.05.003. eCollection 2018 Nov.

Using animal models to determine the significance of complement activation in Alzheimer's disease.利用动物模型确定补体激活在阿尔茨海默病中的意义。

J Neuroinflammation. 2004 Oct 12;1(1):18. doi: 10.1186/1742-2094-1-18.

A lysosomal marker for activated microglial cells involved in Alzheimer classic senile plaques.一种参与阿尔茨海默病典型老年斑形成的活化小胶质细胞的溶酶体标志物。

Acta Neuropathol. 1995;90(5):493-503. doi: 10.1007/BF00294811.

Cellular and substrate adhesion molecules (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease.

Virchows Arch. 1994;424(4):421-7. doi: 10.1007/BF00190565.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验