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倍他洛尔预防放射状角膜切开术后患者类固醇诱导的眼压升高

[Betaxolol for prevention of steroid induced intraocular pressure elevations in patients after radial keratotomy].

作者信息

Kałuzny Bartłomiej J

机构信息

Kliniki Okulistycznej Akademii Medycznej w Bydgoszczy.

出版信息

Klin Oczna. 2003;105(3-4):171-4.

PMID:14552178
Abstract

PURPOSE

To investigate the effect of 0.25% betaxolol (Betoptic S) in the normal myopia eye, on steroid-induced intraocular pressure (IOP) elevations in patients undergoing radial keratotomy.

MATERIAL AND METHODS

Radial keratotomy was performed on 27 patients (43 eyes). All these patients during the period of 3 months after surgery were treated with 0.1% dexamethasone drops in decreasing doses and 0.25% betaxolol (Betoptic S) drops twice a day. Ophthalmic examination and IOP measurements were made on 1, 2, 3, 14, 30, 60 day after operation.

RESULTS

During 3 months of postoperative period 27.9% of eyes had IOP exceeding 25 mm Hg, or had an increase of IOP of 10 mm Hg or more.

CONCLUSIONS

The results of the current study and the study published by the author previously lead to conclusion, that 0.25% betaxolol (Betoptic S) in the normal myopia eye, decreases the risk of steroid-induced IOP elevation in patients after radial keratotomy, but does not prevent it.

摘要

目的

研究0.25%倍他洛尔(贝他舒)对正常近视眼中接受放射状角膜切开术患者的类固醇诱导性眼压升高的影响。

材料与方法

对27例患者(43只眼)进行放射状角膜切开术。所有这些患者在术后3个月期间,均使用剂量递减的0.1%地塞米松滴眼液和每日两次的0.25%倍他洛尔(贝他舒)滴眼液进行治疗。在术后第1、2、3、14、30、60天进行眼科检查和眼压测量。

结果

在术后3个月期间,27.9%的眼睛眼压超过25 mmHg,或眼压升高10 mmHg或更多。

结论

当前研究结果以及作者之前发表的研究得出结论,正常近视眼中的0.25%倍他洛尔(贝他舒)可降低放射状角膜切开术后患者类固醇诱导性眼压升高的风险,但不能预防这种情况。

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