Matzkin D C, Slamovits T L, Genis I, Bello J
Department of Ophthalmology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.
Surv Ophthalmol. 1992 Sep-Oct;37(2):130-6. doi: 10.1016/0039-6257(92)90076-6.
A 30-year-old man presented with monocular visual loss secondary to chronic papilledema, due to an ependymoma involving the spinal cord. No other neurological symptoms were present at the time. Initial neuroradiologic tests as well as laboratory investigations were negative, except for elevated pressure and protein concentration of his cerebrospinal fluid. In spite of intensive investigation, the diagnosis of a spinal cord tumor was delayed for approximately 12 months until he presented with neurologic symptoms attributable to a spinal cord lesion. This is only the fourth case reported of a spinal cord tumor associated with papilledema presenting with visual loss, without any other manifestations of either elevated intracranial pressure, or spinal disease. Possible mechanisms for elevated intracranial pressure in cases of spinal cord tumors are reviewed.
一名30岁男性因脊髓室管膜瘤导致慢性视乳头水肿继发单眼视力丧失。当时无其他神经系统症状。除脑脊液压力和蛋白浓度升高外,初始神经放射学检查及实验室检查均为阴性。尽管进行了深入检查,但脊髓肿瘤的诊断仍延迟了约12个月,直到他出现脊髓病变所致的神经系统症状。这是第四例报告的与视乳头水肿相关的脊髓肿瘤病例,表现为视力丧失,无颅内压升高或脊髓疾病的任何其他表现。本文回顾了脊髓肿瘤患者颅内压升高的可能机制。