Harry T O, Kyari O, Mohammed I
Department of Immunology, University of Maiduguri Teaching Hospital, Nigeria.
Trop Geogr Med. 1992 Jul;44(3):238-41.
A seroepidemiological survey conducted among 1,059 pregnant women in Maiduguri, North-eastern Nigeria from September, 1988 to April, 1990 showed that 5 women or 0.47% were positive for HIV antibodies. Three of the women (0.28%) were positive for HIV-1 while 2 others (0.19%) were positive for HIV-2; this is consistent with the known fact that both viruses are active in West Africa, a sub-region of which Nigeria is part. Detailed information available on 4 of the 5 seropositive women and their husbands did not reveal any known risk factor favouring HIV-infection. In addition to the 5 confirmed seropositive women, 10 others (0.94%) gave Western blot patterns that were neither HIV-1 nor HIV-2. The significance of this observation, if any, needs to be clarified.
1988年9月至1990年4月在尼日利亚东北部迈杜古里对1059名孕妇进行的血清流行病学调查显示,5名女性(0.47%)HIV抗体呈阳性。其中3名女性(0.28%)HIV-1呈阳性,另外2名女性(0.19%)HIV-2呈阳性;这与已知事实相符,即这两种病毒在西非均有活跃传播,尼日利亚是该次区域的一部分。5名血清阳性女性中有4名及其丈夫的详细信息未显示任何有利于HIV感染的已知风险因素。除了这5名确诊的血清阳性女性外,还有10名女性(0.94%)的免疫印迹结果既非HIV-1也非HIV-2。这一观察结果(若有)的意义需要进一步阐明。