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一项对比果纳芬和重组人促卵泡激素高纯度制剂在体外受精(IVF)中使用情况的回顾性研究。

A retrospective review comparing the use of Gonal-F and Metrodin-HP for in-vitro fertilisation (IVF).

作者信息

Lee Colin, Mak F S, Keith J, Welsh D, Yapp Paulina, Chin Rachel

机构信息

Damansara Fertility Centre, 55 Jalan SS21/56B, Damansara Utama, Petaling Jaya, Selangor.

出版信息

Med J Malaysia. 2003 Mar;58(1):94-8.

PMID:14556331
Abstract

All cycles of IVF with pituitary down-regulation (n = 57) done at the Damansara Fertility Centre in the year 2000 were studied. All the 57 patients had controlled ovarian hyperstimulation, either using Metrodin HP (n = 27) or Gonal-F (n = 30). Of these, 53 patients reached oocyte pick-up, 26 patients in Metrodin HP group and 27 patients in Gonal-F group. Gonal-F resulted in a higher clinical pregnancy rate of 66.6% compared to Metrodin HP 38.5% (p < 0.05). The live birth rate tends to be higher in Gonal-F group (40.7%) compared to Metrodin HP (30.8%), (p > 0.05).

摘要

对2000年在白沙罗生育中心进行的所有垂体降调节体外受精周期(n = 57)进行了研究。所有57例患者均接受了控制性卵巢过度刺激,其中27例使用美诺孕(Metrodin HP),30例使用果纳芬(Gonal-F)。其中,53例患者进行了取卵,美诺孕组26例,果纳芬组27例。与美诺孕组的38.5%相比,果纳芬的临床妊娠率更高,为66.6%(p < 0.05)。果纳芬组的活产率(40.7%)与美诺孕组(30.8%)相比有升高趋势(p > 0.05)。

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