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沙特阿拉伯王国哈立德·本·苏丹王子生育中心男性因素夫妇辅助生殖技术的结果

The Outcome of Assisted Reproductive Techniques among Couples with Male Factors at Prince Khalid Bin Sultan Fertility Centre, Kingdom of Saudi Arabia.

作者信息

Mukhtar Hytham Bahaeldin, Shaman Amani, Mirghani Hyder Osman, Almasalmah Ayman Adnan

机构信息

Obstetrics and Gynecology, Faculty of Medicine, University of Tabuk, Tabuk, KSA.

Internal Medicine and Endocrinology, Faculty of Medicine, University of Tabuk, Tabuk, KSA.

出版信息

Open Access Maced J Med Sci. 2017 Aug 6;5(5):603-607. doi: 10.3889/oamjms.2017.102. eCollection 2017 Aug 15.

DOI:10.3889/oamjms.2017.102
PMID:28932299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5591588/
Abstract

BACKGROUND

Thirty-three percent of infertility due to paternal factors, there are an increasing proportion of couples who decide to conceive by assisted reproductive techniques (ART). The outcome prediction is pivotal for decision making.

AIM

We aimed to study the pregnancy outcomes of different ART with male factors infertility.

METHODS

This is retrospective cross-sectional study conducted at Tabuk, Kingdom of Saudi Arabia. One hundred fifteen patients' records reviewed using a structured checklist to collect demographic data, sperm (concentration, motility, and morphology). Female with significant infertility factor were excluded. Chi-square was used for the outcome of various ART.

RESULTS

Out of 115 couples with male factors; treated by Intracytoplasmic Sperm Injection (ICSI), In Vitro Fertilization (IVF) and Intrauterine Insemination (IUI); the mean age was 35.2 ± 6.3 years for men and 29.7 ± 5.1 for females. IVF had the highest success rate overall and had a high pregnancy rate with oligospermia and asthenospermia. ICSI has a good outcome for those with azoospermia, severe oligospermia, and teratozoospermia. IUI must be tried as a first line treatment when semen concentration is more than 10 million sperm/ml. all are not significant (P > 0.05).

CONCLUSION

No significant differences were reported in the pregnancy outcome between various assisted reproductive techniques, smoking, type of infertility and medication.

摘要

背景

因男方因素导致的不孕不育占33%,越来越多的夫妇决定通过辅助生殖技术(ART)受孕。结果预测对于决策至关重要。

目的

我们旨在研究针对男性因素不育的不同辅助生殖技术的妊娠结局。

方法

这是一项在沙特阿拉伯王国塔布克进行的回顾性横断面研究。使用结构化检查表回顾了115例患者的记录,以收集人口统计学数据、精子(浓度、活力和形态)。排除有显著不孕因素的女性。对各种辅助生殖技术的结果使用卡方检验。

结果

在115对有男性因素的夫妇中;接受了卵胞浆内单精子注射(ICSI)、体外受精(IVF)和宫内人工授精(IUI)治疗;男性的平均年龄为35.2±6.3岁,女性为29.7±5.1岁。总体而言,IVF成功率最高,在少精子症和弱精子症患者中妊娠率较高。ICSI对于无精子症、严重少精子症和畸形精子症患者有良好结局。当精液浓度超过1000万精子/毫升时,IUI可作为一线治疗方法尝试。所有差异均无统计学意义(P>0.05)。

结论

在各种辅助生殖技术、吸烟、不孕类型和药物治疗之间,妊娠结局未报告有显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/747a/5591588/062f010ff492/OAMJMS-5-603-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/747a/5591588/2c5fd68f433b/OAMJMS-5-603-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/747a/5591588/062f010ff492/OAMJMS-5-603-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/747a/5591588/2c5fd68f433b/OAMJMS-5-603-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/747a/5591588/062f010ff492/OAMJMS-5-603-g002.jpg

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本文引用的文献

1
A 5-year analysis of semen parameters in Saudi Arabian men attending infertility clinics.对沙特阿拉伯前往不孕不育诊所就诊男性精液参数的5年分析。
J Int Med Res. 2016 Jun;44(3):656-61. doi: 10.1177/0300060516632108. Epub 2016 Apr 1.
2
A unique view on male infertility around the globe.对全球男性不育症的独特见解。
Reprod Biol Endocrinol. 2015 Apr 26;13:37. doi: 10.1186/s12958-015-0032-1.
3
The effects of cigarette smoking on male fertility.吸烟对男性生育能力的影响。
微量元素对沙特不育男性精液氧化状态的影响及其与精子活力的相关性
Saudi J Biol Sci. 2021 Aug;28(8):4455-4460. doi: 10.1016/j.sjbs.2021.04.042. Epub 2021 Apr 24.
4
Live Birth Rate Comparison Between Single vs. Double Ovary Women With Assisted Reproduction: A Single Tertiary Center Study.单卵巢与双卵巢女性辅助生殖的活产率比较:一项单中心三级研究
Cureus. 2021 May 6;13(5):e14876. doi: 10.7759/cureus.14876.
Postgrad Med. 2015 Apr;127(3):338-41. doi: 10.1080/00325481.2015.1015928. Epub 2015 Feb 19.
4
Trends in use of and reproductive outcomes associated with intracytoplasmic sperm injection.卵胞浆内单精子注射的使用趋势及相关生殖结局
JAMA. 2015 Jan 20;313(3):255-63. doi: 10.1001/jama.2014.17985.
5
[Significance of insemination in the era of IVF and ICSI].[体外受精和卵胞浆内单精子注射时代人工授精的意义]
Urologe A. 2010 Jul;49(7):842-6. doi: 10.1007/s00120-009-2219-6.
6
World Health Organization reference values for human semen characteristics.世界卫生组织人类精液特征参考值。
Hum Reprod Update. 2010 May-Jun;16(3):231-45. doi: 10.1093/humupd/dmp048. Epub 2009 Nov 24.
7
Effect of sperm morphology and number on success of intrauterine insemination.精子形态和数量对宫腔内人工授精成功率的影响。
Fertil Steril. 2009 Mar;91(3):777-81. doi: 10.1016/j.fertnstert.2007.12.010. Epub 2008 Mar 4.
8
Assisted reproductive technology and pregnancy outcome.辅助生殖技术与妊娠结局。
Obstet Gynecol. 2005 Nov;106(5 Pt 1):1039-45. doi: 10.1097/01.AOG.0000183593.24583.7c.
9
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10
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J Assist Reprod Genet. 2004 May;21(5):143-8. doi: 10.1023/b:jarg.0000031246.76666.f6.