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肺炎链球菌感染所致肺炎患儿血清抗肺炎球菌荚膜抗体浓度

Serum concentrations of pneumococcal anticapsular antibodies in children with pneumonia associated with Streptococcus pneumonia infection.

作者信息

Esposito Susanna, Droghetti Roberta, Faelli Nadia, Lastrico Annalisa, Tagliabue Claudia, Cesati Laura, Bianchi Ciro, Principi Nicola

机构信息

Pediatric Department I, University of Milan, Italy.

出版信息

Clin Infect Dis. 2003 Nov 1;37(9):1261-4. doi: 10.1086/378740. Epub 2003 Sep 30.

DOI:10.1086/378740
PMID:14557973
Abstract

The levels of specific IgG antibody to pneumococcal capsular polysaccharides were investigated in 182 children, aged 2-5 years, who were hospitalized for community-acquired pneumonia, including 55 (30.2%) with evidence of acute pneumococcal infection. Results show that children with concentrations of specific IgG antibody that would protect against invasive disease do not seem to be protected against pneumonia associated with pneumococcal infection.

摘要

对182名2至5岁因社区获得性肺炎住院的儿童进行了针对肺炎球菌荚膜多糖的特异性IgG抗体水平调查,其中55名(30.2%)有急性肺炎球菌感染的证据。结果显示,具有可预防侵袭性疾病的特异性IgG抗体浓度的儿童似乎并未受到预防与肺炎球菌感染相关肺炎的保护。

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