Tarasów Eugeniusz, Wiercińska-Drapało Alicja, Walecki Jerzy, Prokopowicz Danuta
Zakład Radiologii, Klinika Obserwacyjno-Zakaźna Akademii Medycznej w Białymstoku.
Neurol Neurochir Pol. 2003;37 Suppl 2:21-8.
Changes that may appear in the central nervous system in the course of AIDS either result directly from HIV infection or--as is the case with opportunistic infections and some neoplasms--develop as a secondary consequence of general immunodeficiency. Neuroimaging techniques may be most useful in the differential diagnosis of these lesions. Basic principles of HIV encephalitis and progressive multifocal leukoencephalopathy differentiation in MRI scans are discussed in the paper, and diagnostic possibilities of MR imaging in some other infections (tuberculosis, toxoplasmosis, and cryptococcosis) are outlined. Special attention is paid, on the one hand, to difficulties in the differentiation between toxoplasmosis and lymphoma, and on the other hand--to the growing diagnostic utility of MR-spectroscopy in this respect.
在艾滋病病程中,中枢神经系统可能出现的变化要么直接由HIV感染导致,要么(如机会性感染和一些肿瘤的情况)作为全身免疫缺陷的继发后果而出现。神经影像学技术在这些病变的鉴别诊断中可能最为有用。本文讨论了MRI扫描中HIV脑炎和进行性多灶性白质脑病鉴别的基本原则,并概述了MR成像在其他一些感染(结核病、弓形虫病和隐球菌病)中的诊断可能性。一方面,特别关注弓形虫病和淋巴瘤鉴别的困难,另一方面,关注MR光谱学在这方面日益增长的诊断效用。