Graham John M
UCLH Cochlear Implant Programme, Royal National Throat Nose and Ear Hospital, London, UK.
J Laryngol Otol. 2003 Sep;117(9):675-85. doi: 10.1258/002221503322334477.
The 2002 Graham Fraser Memorial Lecture deals first with the French origins of cochlear implantation in Paris in the 1950s and the role of André Djourno and Charles Eyriès. Following this work in Paris Dr William House in Los Angeles continued work on cochlear implants and, subsequently, experimental implant programmes were started in California, Paris, Vienna and Melbourne. The next section of this lecture covers the experimental work of Galvani in establishing the role of electricity in physiology. The results of his first experiments were published in 1791, the year that Mondini produced the first account of a cochlear malformation in a congenitally deaf child. At around the same time sign language for congenitally deaf children was being developed for the first time in Paris by Epée and the first disputes occurred between oralists and those who promoted signing for the education of congenitally deaf children. In a present day cochlear implant programme good results from implanting congenitally deaf children at an early age and implanting adults who have become profoundly deaf are now taken for granted. We do have much to learn, however, from more complex implant candidates and some examples of such candidates are presented. Lastly, looking to the future, the use of PET scanning to try and gain information about how the brain handles the information provided to it by a cochlear implant is described.
2002年格雷厄姆·弗雷泽纪念讲座首先讲述了20世纪50年代巴黎人工耳蜗植入术的法国起源以及安德烈·乔尔诺和查尔斯·埃里耶的作用。在巴黎的这项工作之后,洛杉矶的威廉·豪斯医生继续进行人工耳蜗的研究,随后,加利福尼亚、巴黎、维也纳和墨尔本都启动了实验性植入项目。讲座的下一部分涵盖了伽伐尼在确立电在生理学中的作用方面的实验工作。他的第一批实验结果于1791年发表,同年蒙迪尼首次描述了一名先天性失聪儿童的耳蜗畸形。大约在同一时间,埃佩在巴黎首次为先天性失聪儿童开发了手语,并且在口语法支持者和提倡使用手语对先天性失聪儿童进行教育的人之间首次出现了争论。在当今的人工耳蜗植入项目中,早期为先天性失聪儿童植入以及为已经完全失聪的成年人植入能取得良好效果,现在这都被视为理所当然。然而,我们确实还有很多要从更复杂的植入候选者身上学习的东西,本文展示了一些这类候选者的例子。最后,展望未来,本文描述了使用正电子发射断层扫描(PET)来试图获取有关大脑如何处理人工耳蜗提供给它的信息的情况。