Jones Andrew O, Kleiman Marc T
Department of Radiation Oncology, Geisinger Medical Center, Danville, PA 17822, USA.
Med Dosim. 2003 Fall;28(3):175-83. doi: 10.1016/S0958-3947(03)00069-4.
Intensity Modulated Radiation Therapy (IMRT) is now widely used in the radiation therapy community. The ability of IMRT to deliver complex dose distributions has allowed dose escalation to targets while sparing normal tissues. In IMRT the roles of the physicist, dosimetrist, and physician are changed. Inverse planning, which is inherent to IMRT, requires that the final dose solution be defined at the beginning of the planning process. The physician must define specific dose volume constraints for the target as well as normal tissues. The physicist and dosimetrist must evaluate the final plan and determine if it meets the goals of the treatment, even if it does not completely satisfy the initial constraints. Once a plan is decided upon, the ability of the clinic to safely and accurately deliver that plan to the patient must be confirmed. As with any new technology, IMRT has created a need for new quality assurance procedures. Here we describe our IMRT process from simulation through planning and treatment. By standardizing our simulations we have decreased setup times and decreased the threat of collisions. Comparison of pseudo-DRR's and multiple-exposure port films allows confirmation of patient positioning on the linac. Our treatment delivery quality assurance program using film and MOSFET detectors in a polystyrene phantom is also described. We provide insight on how to overcome some of the common problems encountered in treatment planning and delivery such as isocenter location, collision avoidance, table indexing, dose confirmation, and plan analysis.
调强放射治疗(IMRT)目前在放射治疗领域得到广泛应用。IMRT能够提供复杂的剂量分布,使得在保护正常组织的同时可提高靶区剂量。在IMRT中,物理师、剂量师和医师的角色发生了变化。IMRT固有的逆向计划要求在计划过程开始时就确定最终的剂量解决方案。医师必须为靶区以及正常组织定义特定的剂量体积约束。物理师和剂量师必须评估最终计划,并确定其是否符合治疗目标,即使它并未完全满足初始约束条件。一旦确定了计划,就必须确认临床机构将该计划安全准确地交付给患者的能力。与任何新技术一样,IMRT催生了对新的质量保证程序的需求。在此,我们描述从模拟到计划及治疗的IMRT流程。通过标准化我们的模拟,我们减少了设置时间并降低了碰撞风险。通过比较伪数字重建影像(DRR)和多次曝光射野片,可以确认患者在直线加速器上的体位。我们还描述了在聚苯乙烯体模中使用胶片和金属氧化物半导体场效应晶体管(MOSFET)探测器的治疗实施质量保证计划。我们提供了关于如何克服治疗计划和实施中遇到的一些常见问题的见解,如等中心定位、避免碰撞、治疗床分度、剂量确认和计划分析。