Neuronal and muscular alterations caused by two wheat endosperm proteins, puroindoline-a and alpha1-purothionin, are due to ion pore formation.
作者信息
Llanos Paola, Henriquez Mauricio, Minic Jasmina, Elmorjani Khalil, Marion Didier, Riquelme Gloria, Molgó Jordi, Benoit Evelyne
机构信息
Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Independencia No. 1027, Casilla 70005, Santiago 6530499, Chile.
出版信息
Eur Biophys J. 2004 May;33(3):283-4. doi: 10.1007/s00249-003-0353-4. Epub 2003 Oct 15.
PMID:14564416
Abstract
Using the patch-clamp technique it was found that the toxicity of the two wheat endosperm proteins puroindoline-a and alpha1-purothionin probably results from the dissipation of ion concentration gradients essential for the maintenance of cellular homeostasis.
摘要
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