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使用可扩张针进行肝脏局灶性恶性肿瘤的射频热消融:并发症报告

Radiofrequency thermal ablation with expandable needle of focal liver malignancies: complication report.

作者信息

Buscarini Elisabetta, Buscarini Luigi

机构信息

Department of Gastroenterology, General Hospital, Via Macallé 1, 26013, Crema, Italy.

出版信息

Eur Radiol. 2004 Jan;14(1):31-7. doi: 10.1007/s00330-003-1990-9. Epub 2003 Oct 17.

DOI:10.1007/s00330-003-1990-9
PMID:14564470
Abstract

The aim of this study was to describe type and rate of complications in a series of patients with liver tumors treated by the radiofrequency (RF) expandable system. A total of 166 patients, 114 with hepatocellular carcinoma (HCC; 92 small HCC, 22 large) and 52 with liver metastasis, were treated by the percutaneous RF expandable system. In large HCCs, RF ablation was performed after tumor ischemia (TAE or balloon stop flow of the hepatic artery). Major complications were those that delayed hospital discharge, with or without additional medical procedures or treatments. Minor complications did not require an additional hospital stay. No deaths occurred. Among 151 patients followed, there were 7 (4.6%) early major complications-severe pain with session interruption in 3 cases, capsular necrosis in 1 case, 1 abdominal wall necrosis, 1 dorsal burning, 1 peritoneal hemorrhage-and 3 (1.9%) delayed major complications: sterile fluid collection at the site of the treated tumor in 2 cases and cutaneous seeding in 1 case. There were 49 (32.5%) minor complications. The complication rate is similar to that observed after percutaneous alcohol injection (PEI). With the cooled system, the complication rate is seemingly lower but that may well be due to a different definition of major complications. The seeding rate after expandable system ablation is lower than after PEI. It is the same as or lower than that in other series of patients treated by the cooled system.

摘要

本研究旨在描述一系列接受射频(RF)可扩展系统治疗的肝肿瘤患者的并发症类型及发生率。共有166例患者接受了经皮RF可扩展系统治疗,其中114例为肝细胞癌(HCC;92例小肝癌,22例大肝癌),52例为肝转移瘤。对于大肝癌,在肿瘤缺血(经动脉化疗栓塞或肝动脉球囊阻断血流)后进行射频消融。主要并发症是那些导致出院延迟的情况,无论是否需要额外的医疗程序或治疗。次要并发症则无需额外住院。无死亡病例发生。在151例接受随访的患者中,有7例(4.6%)发生早期主要并发症——3例因严重疼痛导致治疗中断,1例包膜坏死,1例腹壁坏死,1例背部灼伤,1例腹膜出血——以及3例(1.9%)延迟主要并发症:2例在治疗肿瘤部位出现无菌性积液,1例皮肤种植转移。有49例(32.5%)发生次要并发症。并发症发生率与经皮酒精注射(PEI)后观察到的相似。使用冷却系统时,并发症发生率似乎较低,但这很可能是由于对主要并发症的定义不同。可扩展系统消融后的种植转移率低于PEI后的。与其他接受冷却系统治疗的患者系列相同或更低。

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Eur Radiol. 2001;11(10):2102-8. doi: 10.1007/s003300100973.
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Percutaneous radio-frequency ablation of hepatic metastases from colorectal cancer: long-term results in 117 patients.
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Cancers (Basel). 2022 Oct 23;14(21):5198. doi: 10.3390/cancers14215198.
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Interv Radiol (Higashimatsuyama). 2020 Jun 30;5(2):50-57. doi: 10.22575/interventionalradiology.2020-0008.
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