Gintsburg A L, Il'ina T S, Romanova Iu M
Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 2003 Sep-Oct(5):86-93.
The review deals with the data of literature on the role of the "quorum sensing" (QS) system ensuring the social behavior of bacteria in the regulation of virulence genes. The mechanisms of the action of these systems in Gram-negative and Gram-positive bacteria, as well as the influence of acyl-homoserine lactones, one of the components of the QS system, on the immune response of the infected host are discussed. In addition, in this review the data of literature on the existence of bacteria in the form of biofilms are presented. The methods of the identification of biofilms, the methods of their experimental preparation and the role of the QS system in the process of their formation are considered.
这篇综述探讨了关于“群体感应”（QS）系统在调控毒力基因中确保细菌社会行为作用的文献数据。讨论了这些系统在革兰氏阴性菌和革兰氏阳性菌中的作用机制，以及QS系统的组成成分之一酰基高丝氨酸内酯对受感染宿主免疫反应的影响。此外，本综述还介绍了关于细菌以生物膜形式存在的文献数据。考虑了生物膜的鉴定方法、其实验制备方法以及QS系统在其形成过程中的作用。
