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胍磷菌素的合成研究:通过光延反应对8-氧代嘌呤核苷进行糖基化反应。

Synthetic studies on guanofosfocin: glycosylation of 8-oxo-purine nucleosides via Mitsunobu reaction.

作者信息

Sugimura Hideyuki, Koizumi Akiyoshi, Kiyohara Wataru

机构信息

Faculty of Education and Human Science, Yokohama National University, Hodogaya-ku, Yokohama, Japan.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):727-9. doi: 10.1081/NCN-120022620.

Abstract

In model studies directed to the total synthesis of guanofosfocins, a unique glycosidic bond formation between the 8-oxo-purine nucleosides and mannopyranose derivatives under Mistunobu conditions is described.

摘要

在针对鸟嘌呤磷霉素全合成的模型研究中,描述了在光延条件下8-氧代嘌呤核苷与吡喃甘露糖衍生物之间独特的糖苷键形成。

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