2',3'-二脱氧-2'-氟-3'-C-羟甲基-β-D-阿拉伯呋喃糖基嘧啶核苷的合成与抗病毒活性评价
Synthesis and antiviral evaluation of 2',3'-dideoxy-2'-fluoro-3'- C-hydroxymethyl-beta-D-arabinofuranosyl pyrimidine nucleosides.
作者信息
Hassan Abdalla E A, Pai Balakrina S, Lostia Stefania, Stuyver Lieven, Otto Michael J, Schinazi Raymond F, Watanabe Kyoichi A
机构信息
Pharmasset Inc., Tucker, Georgia 30084, USA.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):891-4. doi: 10.1081/NCN-120022679.
PMID:14565304
Abstract
The synthesis and anti-HBV and anti-HIV activity of a number of 2',3'-dideoxy-2'-fluoro-3'-C-hydroxymethyl-beta-D-arabinofuranosyl pyrimidine nucleosides are reported.
摘要
报道了多种2'，3'-二脱氧-2'-氟-3'-C-羟甲基-β-D-阿拉伯呋喃糖基嘧啶核苷的合成及其抗乙肝病毒和抗艾滋病毒活性。
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