xylo-configured oligonucleotides (XNA, xylo nucleic acids): synthesis and hybridization studies.
作者信息
Poopeiko Nicolai E, Dahl Britta M, Wengel Jesper
机构信息
Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1147-9. doi: 10.1081/NCN-120022822.
PMID:14565366
Abstract
We report synthesis and high-affinity hybridization of fully modified home-thymine 2'-deoxy and 2'-deoxy-2'-fluoro xylo nucleic acids.
摘要
相似文献
1
xylo-configured oligonucleotides (XNA, xylo nucleic acids): synthesis and hybridization studies.
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1147-9. doi: 10.1081/NCN-120022822.
2
Xylo-Configured oligonucleotides (XNA, xylo nucleic acid): synthesis of conformationally restricted derivatives and hybridization towards DNA and RNA complements.木糖构型的寡核苷酸（XNA，木糖核酸）：构象受限衍生物的合成及其与DNA和RNA互补链的杂交
Bioorg Med Chem Lett. 2003 Jul 21;13(14):2285-90. doi: 10.1016/s0960-894x(03)00441-4.
3
Stabilisation of nucleic acid secondary structures by oligonucleotides with an additional nucleobase; synthesis and incorporation of 2'-deoxy-2'-C-(2-(thymine-1-yl)ethyl)uridine.带有额外碱基的寡核苷酸对核酸二级结构的稳定作用；2'-脱氧-2'-C-(2-(胸腺嘧啶-1-基)乙基)尿苷的合成与掺入
Org Biomol Chem. 2005 Oct 7;3(19):3570-5. doi: 10.1039/b510167k. Epub 2005 Sep 2.
4
2'-modified-2-thiothymidine oligonucleotides.2'-修饰的2-硫代胸苷寡核苷酸
Org Lett. 2003 Aug 21;5(17):3005-8. doi: 10.1021/ol0348607.
5
Synthesis and structural characterization of 2'-fluoro-α-L-RNA-modified oligonucleotides.2'-氟-α-L-RNA 修饰寡核苷酸的合成与结构表征。
Chembiochem. 2011 Aug 16;12(12):1904-11. doi: 10.1002/cbic.201100161. Epub 2011 Jul 4.
6
A new route to 2'-O-alkyl-2-thiouridine derivatives via 4-O-protection of the uracil base and hybridization properties of oligonucleotides incorporating these modified nucleoside derivatives.一种通过尿嘧啶碱基的4-O-保护合成2'-O-烷基-2-硫代尿苷衍生物的新途径以及掺入这些修饰核苷衍生物的寡核苷酸的杂交特性。
J Org Chem. 2003 Dec 26;68(26):9971-82. doi: 10.1021/jo035246b.
7
Synthesis and hybridization studies of alpha-configured arabino nucleic acids.α构型阿拉伯糖核酸的合成与杂交研究
Org Biomol Chem. 2009 Jun 7;7(11):2389-401. doi: 10.1039/b905019c. Epub 2009 Apr 15.
8
(1S,2R/1R,2S)-ainocyclohexyl glycyl thymine PNA: synthesis, monomer crystal structures, and DNA/RNA hybridization studies.(1S,2R/1R,2S)-氨基环己基甘氨酰胸腺嘧啶肽核酸：合成、单体晶体结构及DNA/RNA杂交研究
Org Lett. 2003 Aug 21;5(17):3013-6. doi: 10.1021/ol034933m.
9
2'-O-[2-(guanidinium)ethyl]-modified oligonucleotides: stabilizing effect on duplex and triplex structures.2'-O-[2-(胍基)乙基]修饰的寡核苷酸：对双链和三链结构的稳定作用。
Org Lett. 2004 Jun 10;6(12):1971-4. doi: 10.1021/ol049470e.
10
LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.锁核酸（LNA）：对互补RNA和DNA的高亲和力靶向作用。
Biochemistry. 2004 Oct 26;43(42):13233-41. doi: 10.1021/bi0485732.
Zotero 插件