Towards a DNA-like duplex without hydrogen bonds.
作者信息
Mathis Gérald, Schütz Rolf, Hunziker Jürg
机构信息
Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1183-5. doi: 10.1081/NCN-120022831.
PMID:14565375
Abstract
The inverse quadrupolar moments of the phenyl and pentafluorophenyl residues in the base pair P-F5 promotes strong intramolecular stacking interactions in DNA duplexes. The more natural base pairs are replaced by this novel pair the higher the thermodynamic stability of the resulting duplex if they are arranged in an alternating fashion.
摘要
Zotero 插件