A novel and convenient method for the synthesis of free 5'-thiol modified oligonucleotides.
作者信息
Kupihár Z, Kovács G, Kele Z, Darula Z, Kovács L
机构信息
Nucleic Acids Laboratory, Department of Medicinal Chemistry, University of Szeged, Szeged, Hungary.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1297-9. doi: 10.1081/NCN-120022950.
PMID:14565403
Abstract
The synthesis of free 5'-thiol-modified oligonucleotides using a 4,4',4''-trimethoxytrityl (TMTr)-protected linker and standard Poly-Pak purification has been described.
摘要
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