一名患有艾滋病相关卡波西肉瘤的患者发生快速进展的人疱疹病毒8相关实体间变性淋巴瘤。
Rapidly progressive human herpesvirus 8-associated solid anaplastic lymphoma in a patient with AIDS--associated Kaposi sarcoma.
作者信息
Yamamoto Yoshihiko, Teruya Katsuji, Katano Harutaka, Niino Hitoshi, Yasuoka Akira, Kimura Satoshi, Oka Shinichi
机构信息
AIDS Clinical Center, International Medical Center of Japan, Toyama 1-21-1, Toyama, Shinjuku, Tokyo 162-8655, Japan.
出版信息
Leuk Lymphoma. 2003 Sep;44(9):1631-3. doi: 10.3109/10428190309178791.
We report a case of rapidly progressive solid lymphoma with anaplastic large cell morphology, followed by systemic Kaposi sarcoma in an adult patient with AIDS. The lymphoma cells expressed human herpesvirus 8 (HHV-8)-encoded latent and lytic proteins and Epstein-Barr virus-encoded small RNA, suggesting that this case could be categorized into HHV-8-associated solid lymphoma, a recently identified disease entity.
我们报告了一例具有间变性大细胞形态的快速进展性实体淋巴瘤病例，该病例发生在一名患有艾滋病的成年患者身上，随后发展为系统性卡波西肉瘤。淋巴瘤细胞表达了人类疱疹病毒8（HHV-8）编码的潜伏和裂解蛋白以及爱泼斯坦-巴尔病毒编码的小RNA，这表明该病例可归类为HHV-8相关实体淋巴瘤，这是一种最近发现的疾病实体。
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