Negreira Cepeda S, López López A, Fernández-Cuesta Valcarce M A, Cano Novillo I, Nogales Espert A
Unidad de Lactantes, Departamento de Pediatría, Hospital 12 de Octubre, Madrid.
An Esp Pediatr. 1992 Nov;37(5):383-6.
We have studied the clinical profile, cause and outcome of 105 infants with the diagnosis of gastroesophageal reflux. In most cases, pharmacological treatment managed to control the symptoms in 9 out of 10 infants followed in our series. Complications were described in 26.2%, of which esophagitis and chronic respiratory disease were the most common. Corrective surgery of the reflux was indicated in those cases in which pharmacological treatment was not successful. This managed to control the reflux in 90% of all cases. Morbidity was scarce. In all, 75% of the infants were considered to be medically cured within 15.5 months from the time that they were diagnosed and within 18.5 months after the appearance of the first symptoms.
我们研究了105例诊断为胃食管反流的婴儿的临床特征、病因及转归。在我们的系列研究中,大多数情况下,药物治疗成功控制了十分之九接受随访婴儿的症状。26.2%的病例出现了并发症,其中食管炎和慢性呼吸道疾病最为常见。对于药物治疗不成功的病例,需进行反流矫正手术。这成功控制了所有病例中90%的反流。发病率很低。总体而言,75%的婴儿在确诊后15.5个月内以及首次出现症状后18.5个月内被认为已临床治愈。