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[胰腺分裂症、慢性胰腺炎与糖尿病。胰空肠吻合术的改善作用]

[Pancreas divisum, chronic pancreatitis and diabetes mellitus. Improvement by pancreaticojejunostomy].

作者信息

Wind P, Berger A, Chevallier J M, Frileux P, Cugnenc P H

机构信息

Service de Chirurgie Digestive et Générale, Hôpital Laënnec, Paris.

出版信息

Ann Chir. 1992;46(7):625-9.

PMID:1456695
Abstract

The relationship between pancreas divisum and chronic pancreatitis is controversial. We report the cases of two patients aged 40 and 53 years suffering from recurrent pancreatitis and known to have histologically proven idiopathic chronic pancreatitis. One patient had insulin dependent diabetes. Pancreatography demonstrated in these two cases a pancreas divisum with a dilated dorsal pancreatic duct. A pancreatico-jejunostomy was performed, associated in one case with splenopancreatectomy for pseudo-cyst. With a follow-up of 32 and 78 months, both patients were free of symptoms and the diabetic patient had normal blood glucose levels with diet alone. The clinical history of the patients suggests a relationship between pancreas divisum and chronic pancreatitis and that pancreatico-jejunostomy may improve pancreatic pain and pancreatic function.

摘要

胰腺分裂与慢性胰腺炎之间的关系存在争议。我们报告了两名年龄分别为40岁和53岁的患者,他们患有复发性胰腺炎,经组织学证实为特发性慢性胰腺炎。其中一名患者患有胰岛素依赖型糖尿病。胰管造影显示这两名患者均为胰腺分裂,伴有背侧胰管扩张。进行了胰空肠吻合术,其中一例因假性囊肿行脾胰切除术。随访32个月和78个月后,两名患者均无症状,糖尿病患者仅通过饮食血糖水平就恢复正常。患者的临床病史表明胰腺分裂与慢性胰腺炎之间存在关联,并且胰空肠吻合术可能会改善胰腺疼痛和胰腺功能。

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