Keith R G, Shapero T F, Saibil F G
Can J Surg. 1982 Nov;25(6):622-6.
Of 480 patients seen with pancreatitis at the Sunnybrook Medical Centre, Toronto, in the past 5 years, 5 had pancreas divisum, demonstrated by pancreatography. Clinical presentations included recurrent acute pancreatitis, chronic pancreatitis and recurrent subcutaneous fat necrosis with steatorrhea. Pancreatography demonstrated dorsal pancreatic drainage through the duct of Santorini in all cases. The luminal diameter at the orifice of the duct of Santorini, assessed at operation, was inadequate to provide normal drainage from the gland. Sphincterotomy of the duct of Santorini alone, without surgery to the duct of Wirsung or sphincter of Oddi, was performed in four patients. This relieved the pain of chronic pancreatitis, eliminated recurrent attacks of acute pancreatitis and curtailed recurrence of subcutaneous fat necrosis and steatorrhea during follow-up periods of 51, 27, 17 and 28 months respectively. One patient who refused operation continued to have recurrent pancreatitis 41 months after diagnosis.
在过去5年中,多伦多桑尼布鲁克医疗中心收治了480例胰腺炎患者,其中5例经胰管造影显示为胰腺分裂症。临床表现包括复发性急性胰腺炎、慢性胰腺炎以及伴有脂肪泻的复发性皮下脂肪坏死。胰管造影显示所有病例中背侧胰腺均通过Santorini管引流。术中评估Santorini管开口处的管腔直径不足以提供正常的胰腺引流。4例患者仅对Santorini管进行了括约肌切开术,未对Wirsung管或Oddi括约肌进行手术。这缓解了慢性胰腺炎的疼痛,消除了急性胰腺炎的复发,并分别在51个月、27个月、17个月和28个月的随访期内减少了皮下脂肪坏死和脂肪泻的复发。1例拒绝手术的患者在诊断后41个月仍有复发性胰腺炎。