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Glucose autoxidation produces acrolein from lipid peroxidation in vitro.

作者信息

Medina-Navarro Rafael, Durán-Reyes Genoveva, Díaz-Flores Margarita, Kumate Rodríguez Jesús, Hicks Juan José

出版信息

Clin Chim Acta. 2003 Nov;337(1-2):183-5. doi: 10.1016/j.cccn.2003.07.005.

DOI:10.1016/j.cccn.2003.07.005
PMID:14568199
Abstract
摘要

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Current status of acrolein as a lipid peroxidation product.丙烯醛作为脂质过氧化产物的现状。
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Identification of acrolein from the ozone oxidation of unsaturated fatty acids.从不饱和脂肪酸的臭氧氧化反应中鉴定出丙烯醛。
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Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of inflammation.人类中性粒细胞利用髓过氧化物酶-过氧化氢-氯化物系统将羟基氨基酸转化为乙醇醛、2-羟基丙醛和丙烯醛。这是一种吞噬细胞在炎症部位生成高反应性α-羟基和α,β-不饱和醛的机制。
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