Zardo Mariani Schlabendorff, Procianoy Renato S
Serviço de Neonatologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.
Rev Saude Publica. 2003 Oct;37(5):591-6. doi: 10.1590/s0034-89102003000500007. Epub 2003 Oct 9.
To evaluate and compare birthweight and scores as predictors of neonatal mortality in a Neonatal Intensive Care Unit (NICU).
The survey included 494 newborns admitted to the neonatal intensive care unit (NICU) of a general hospital in Porto Alegre, southern Brazil, immediately after delivery, between March 1997 and June 1998. Birthweight and scores were evaluated in terms of the variable "death while in NICU". Exclusion criteria were: discharge or death less than 24 hours after admission, admission not immediately following delivery, incomplete study protocol, and congenital malformations incompatible with survival. For CRIB (Clinical Risk Index for Babies) evaluation purposes, only patients born weighing up to 1,500 g were considered. ROC (Receiver Operating Characteristics) curves were calculated for SNAP (Score for Neonatal Acute Physiology), SNAP-PE (Score for Neonatal Acute Physiology--Perinatal Extension), SNAP II, SNAP-PE II, and CRIB scores, as well as for birthweight.
Of the 494 patients studied, 44 died (8.9% mortality). Of the 102 patients born weighing up to 1,500 g, 32 (31.3%) died. The area below the ROC curves ranged from 0.81 to 0.94. There were no statistically significant differences between the areas obtained for all scores evaluated. All mortality risk scores evaluated performed better than birthweight, especially on newborns with birthweight=1,500 g.
All neonatal mortality scores had better performance and were superior to birthweight as measures of in-hospital mortality risk for newborns admitted to NICU.
评估并比较出生体重和评分作为新生儿重症监护病房(NICU)新生儿死亡率预测指标的情况。
该调查纳入了1997年3月至1998年6月间在巴西南部阿雷格里港一家综合医院新生儿重症监护病房(NICU)分娩后立即入院的494例新生儿。根据“在NICU期间死亡”这一变量对出生体重和评分进行评估。排除标准为:入院后24小时内出院或死亡、非分娩后立即入院、研究方案不完整以及与生存不相容的先天性畸形。为进行CRIB(婴儿临床风险指数)评估,仅考虑出生体重达1500g的患者。计算了SNAP(新生儿急性生理学评分)、SNAP - PE(新生儿急性生理学 - 围产期扩展评分)、SNAP II、SNAP - PE II和CRIB评分以及出生体重的ROC(受试者工作特征)曲线。
在研究的494例患者中,44例死亡(死亡率8.9%)。在102例出生体重达1500g的患者中,32例(31.3%)死亡。ROC曲线下面积范围为0.81至0.94。所有评估评分所获得的面积之间无统计学显著差异。所有评估的死亡风险评分表现均优于出生体重,尤其是对于出生体重 = 1500g的新生儿。
作为NICU收治新生儿院内死亡风险的衡量指标,所有新生儿死亡率评分表现更佳且优于出生体重。