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利用 SNAP II 和 SNAPPE II 评分预测伊朗新生儿队列的死亡率。

Utilization of SNAP II and SNAPPE II Scores for Predicting the Mortality Rate Among a Cohort of Iranian Newborns.

机构信息

Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Neonatal Health Research Center (NHRC), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Arch Iran Med. 2018 Apr 1;21(4):153-157.

Abstract

BACKGROUND

The present study was conducted to determine the utility of Score for Neonatal Acute Physiology II (SNAP II) and Score for Neonatal Acute Physiology with Perinatal Extension II (SNAPPE II) scoring systems as predictors of neonatal mortality rate, and to compare the predictive value of these two methods.

METHODS

In this prospective study data were gathered from infants admitted to the neonatal intensive care unit (NICU) of Imam Hossein Medical Center, Tehran, Iran, from March 2015 to December 2015. In addition to demographic data, Apgar score at 5 minutes after birth, initial and final diagnosis, SNAP II, and SNAPPE II were recorded within 24 hours after admission to the NICU.

RESULTS

One hundred ninety-one newborn infants entered into the study. Birth weight (2555 ± 722 g in survival group versus 1588 ± 860 g in expired group, P<0.001), and Apgar score more than 7 at 5 minutes after birth (99.4% in survival group versus 57.1% in expired group, P<0.001) were significantly related to the mortality rate. By analyzing the data using logistic regression, it was found that SNAP II (area under the curve [AUC] = 0.992; 95% CI: 0.98-1) and SNAPPE II (AUC = 0.994; 95% CI: 0.984-1)had better value for predicting the patients' survival compared to Apgar score at 5 minutes after birth (AUC = 0.711; 95% CI: 0.568-0.855). There was no statistically significant difference in predictive value of SNAP II and SNAPPE II methods (P>0.99).

CONCLUSION

According to our findings SNAP II and SNAPPE II are useful tools in predicting the mortality rate among Iranian neonates admitted to NICU. Although there was no significant difference between SNAP II and SNAPPE II, both methods had a much better predictive value compared to Apgar score at 5 minutes after birth.

摘要

背景

本研究旨在确定新生儿急性生理学评分 II(SNAP II)和新生儿急性生理学与围产期扩展评分 II(SNAPPE II)评分系统作为新生儿死亡率预测指标的效用,并比较这两种方法的预测价值。

方法

在这项前瞻性研究中,数据来自 2015 年 3 月至 2015 年 12 月期间入住伊朗德黑兰伊玛目侯赛因医疗中心新生儿重症监护病房(NICU)的婴儿。除了人口统计学数据外,还在入院后 24 小时内记录了出生后 5 分钟的 Apgar 评分、初始和最终诊断、SNAP II 和 SNAPPE II。

结果

191 名新生儿进入研究。出生体重(存活组为 2555±722g,死亡组为 1588±860g,P<0.001)和出生后 5 分钟 Apgar 评分大于 7(存活组为 99.4%,死亡组为 57.1%,P<0.001)与死亡率显著相关。通过使用逻辑回归分析数据,发现 SNAP II(曲线下面积 [AUC] = 0.992;95%CI:0.98-1)和 SNAPPE II(AUC = 0.994;95%CI:0.984-1)在预测患者生存率方面的价值优于出生后 5 分钟 Apgar 评分(AUC = 0.711;95%CI:0.568-0.855)。SNAP II 和 SNAPPE II 方法的预测价值无统计学差异(P>0.99)。

结论

根据我们的发现,SNAP II 和 SNAPPE II 是预测伊朗 NICU 新生儿死亡率的有用工具。虽然 SNAP II 和 SNAPPE II 之间没有显著差异,但与出生后 5 分钟 Apgar 评分相比,这两种方法的预测价值都要好得多。

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