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不同剂量及机体放射性核素平衡条件下,小林姬鼠各组织中异常细胞的水平。

The level of aberrant cells in various tissues of bank vole depending on doses and radionuclide balance in organism.

作者信息

Voitovich A M, Afonin V Yu, Krupnova E V, Trusova V D, Dromashko E S

机构信息

Academy of Sciences of Belarus, Minsk.

出版信息

Tsitol Genet. 2003 Jul-Aug;37(4):10-5.

Abstract

A regression analysis shows the direct linear relation between 137Cs accumulation in rodents and the level of aberrant cells. For 90Sr this trend was negative. The dose relationship was the same with 137Cs. The trends were negative 1 month later after feeding of animals with clean food. Correspondingly the dose relationship was also negative. The levels of cells with apoptosis features were different in animals from the control and the radiocontaminated sites. The analysis has revealed the correlation between the 90Sr content in animal body and the number of alveolar macrophages containing micronuclei. The relationship was revealed between the 137Cs content in the animal body and the number of intestinal epithelial cells with micronuclei.

摘要

回归分析表明,啮齿动物体内137Cs的积累与异常细胞水平之间存在直接线性关系。对于90Sr,这种趋势是负相关的。137Cs的剂量关系也是如此。在用清洁食物喂养动物1个月后,这些趋势变为负相关。相应地,剂量关系也呈负相关。来自对照和放射性污染地点的动物体内具有凋亡特征的细胞水平不同。分析揭示了动物体内90Sr含量与含有微核的肺泡巨噬细胞数量之间的相关性。还揭示了动物体内137Cs含量与含有微核的肠上皮细胞数量之间的关系。

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