White Paul F, Issioui Tijani, Skrivanek Gary D, Early John S, Wakefield Cynthia
Departments of *Anesthesiology and Pain Management and †Orthopedic Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Anesth Analg. 2003 Nov;97(5):1303-1309. doi: 10.1213/01.ANE.0000082242.84015.D4.
Popliteal sciatic nerve block is a commonly used technique for surgery involving the foot and ankle. However, pain can be difficult to control as the local anesthetic block wears off. Therefore, we hypothesized that extending the block by using a continuous infusion of bupivacaine (0.25%) would provide improved pain management and might facilitate the recovery process after foot or ankle surgery. In this randomized, double-blinded, placebo-controlled study, 24 consenting patients undergoing foot or ankle surgery with a standardized general anesthetic technique were studied. Before surgery, a popliteal sciatic nerve block was performed in all patients with an 18-gauge Tuohy epidural needle and a peripheral nerve stimulator. After injection of bupivacaine 0.25% 30 mL and placement of a 20-gauge catheter, patients were randomly assigned to receive either 0.9% saline (control) or bupivacaine 0.25% at a constant rate of 5 mL/h for up to 48 h after surgery. An 11-point verbal rating scale (0 = no pain to 10 = worst pain imaginable) was used to assess the severity of pain. Opioid analgesic use was recorded at specific time intervals after surgery. Follow-up evaluations were performed at 24 h, 48 h, 72 h, and 1 week after surgery to assess pain scores, as well as patient satisfaction with their pain management and quality of recovery, by using a 100-point verbal rating scale (1 = highly dissatisfied to 100 = highly satisfied). In the bupivacaine group, there was a statistically significant reduction in the maximal pain scores (>50%) and in opioid use (>60%) during the postoperative period compared with the control group. Patient satisfaction with postoperative pain management (95 +/- 3 versus 77 +/- 13) and quality of recovery (96 +/- 7 versus 83 +/- 14) was significantly improved in the bupivacaine group (versus control). In addition, 40% of the patients in the bupivacaine group (versus none in the control group) were able to be discharged home on the day of surgery (P = 0.087). In conclusion, a continuous infusion of bupivacaine 0.25% decreased postoperative pain and the need for opioid analgesic rescue medication after orthopedic surgery involving the foot and ankle, leading to improved patient satisfaction and quality of recovery.
A continuous infusion of bupivacaine 0.25% (versus saline) at the popliteal fossa by using a simple elastomeric pump is an effective method of decreasing postoperative pain, reducing the opioid analgesic requirement, and increasing patient satisfaction with pain management after orthopedic surgery involving the foot and ankle. More importantly, the use of the continuous sciatic nerve block in the popliteal fossa facilitated an earlier discharge after lower extremity surgery.
腘窝坐骨神经阻滞是一种常用于足部和踝部手术的技术。然而,随着局部麻醉阻滞作用消退,疼痛可能难以控制。因此,我们推测通过持续输注布比卡因(0.25%)来延长阻滞时间可改善疼痛管理,并可能促进足部或踝部手术后的恢复过程。在这项随机、双盲、安慰剂对照研究中,对24例同意采用标准化全身麻醉技术接受足部或踝部手术的患者进行了研究。手术前,所有患者均使用18号Tuohy硬膜外针和外周神经刺激器进行腘窝坐骨神经阻滞。注射0.25%布比卡因30 mL并置入20号导管后,患者被随机分配接受0.9%生理盐水(对照组)或0.25%布比卡因,术后以5 mL/h的恒定速率持续输注长达48小时。采用11分数字评定量表(0 = 无痛至10 = 难以想象的剧痛)评估疼痛严重程度。记录术后特定时间间隔使用阿片类镇痛药的情况。术后24小时、48小时、72小时和1周进行随访评估,通过100分数字评定量表(1 = 非常不满意至100 = 非常满意)评估疼痛评分、患者对疼痛管理的满意度及恢复质量。与对照组相比,布比卡因组术后期间最大疼痛评分(>50%)和阿片类药物使用量(>60%)有统计学显著降低。布比卡因组患者对术后疼痛管理的满意度(95±3对77±13)和恢复质量(96±7对83±14)较对照组有显著改善。此外,布比卡因组40%的患者(对照组无患者)能够在手术当天出院(P = 0.087)。总之,持续输注0.25%布比卡因可减轻足部和踝部骨科手术后的疼痛以及对阿片类镇痛药的需求,提高患者满意度和恢复质量。
通过简单的弹性泵在腘窝持续输注0.25%布比卡因(与生理盐水相比)是减轻术后疼痛、减少阿片类镇痛药需求并提高足部和踝部骨科手术后患者对疼痛管理满意度的有效方法。更重要的是,在腘窝使用持续坐骨神经阻滞有助于下肢手术后更早出院。