Terada Kihei, Niizuma Takahiro, Ogita Satoko, Kataoka Naoki
Kawasaki Medical School, Department of Pediatrics.
Kansenshogaku Zasshi. 2003 Sep;77(9):667-72. doi: 10.11150/kansenshogakuzasshi1970.77.667.
Although there have been measles outbreaks involving more than 100,000 patients every few years in Japan, vaccination is not compulsory under Japanese law and the vaccination rate remains low. In addition, because MMR vaccines have been suspended due to complications, monovalent measles vaccine is still used and administered only once for life. Under these circumstances, a new system was started to develop motivation for vaccination in order to try to eliminate measles and rubella. Although educational campaigns for vaccination are important, their effect is frequently temporary. To maintain a high vaccination rate after such campaigns, we advocated checking children for susceptibility, recommended vaccination and asked for certificates of vaccination at school entry. The participating subjects were 65/68 kindergartens, 55/55 primary schools and 24/24 junior high schools in Kurashiki City, Japan. The total number of subjects was 11,365. The susceptibility rate for measles and the unknown rate were 5.6% and 2.0% at kindergartens, 4.6% and 4.4% at primary schools, and 3.0% and 8.3% at junior high schools, whereas the susceptibility rate for rubella and the unknown rate were 14.0% and 2.3% at kindergartens, 21.8% and 5.4% at primary schools, and 35.2% and 11.7% at junior high schools. Among the children who were susceptible to measles, we confirmed that a certificate of vaccination was presented by 38.0% of pupils in kindergartens, 85.3% of those in primary schools and 43.7% of those in junior high schools. As for rubella, we confirmed 21.8% presented a certificate in kindergartens, 28.6% in primary schools and 11.6% in junior high schools. As a result, we achieved our goal for measles, which was previously determined as more than 90% for students with past history of infection or vaccination. However, we could not attain our goal for rubella. These systems were more effective than educational campaigns alone and were thought to increase the motivation for vaccination through their continuation. The rate of those who could not receive the vaccination due to allergy or seizure among the susceptible was 26% in total but more than 40% in some schools. We should educate not only parents but also doctors regarding vaccination and advocate that it be done.
尽管日本每隔几年就会出现涉及超过10万名患者的麻疹疫情,但根据日本法律,疫苗接种并非强制要求,接种率仍然很低。此外,由于MMR疫苗因并发症而暂停使用,目前仍使用单价麻疹疫苗,且一生仅接种一次。在这种情况下,为了努力消除麻疹和风疹,启动了一个新的系统来提高疫苗接种的积极性。尽管疫苗接种教育活动很重要,但其效果往往是暂时的。为了在这类活动后保持高接种率,我们主张对儿童进行易感性检查,推荐接种疫苗,并要求在入学时提供疫苗接种证明。参与的对象是日本仓敷市的65/68所幼儿园、55/55所小学和24/24所初中。对象总数为11365人。幼儿园的麻疹易感性率和未知率分别为5.6%和2.0%,小学为4.6%和4.4%,初中为3.0%和8.3%;而风疹的易感性率和未知率在幼儿园分别为14.0%和2.3%,小学为21.8%和5.4%,初中为35.2%和11.7%。在易感染麻疹的儿童中,我们确认幼儿园38.0%的学生、小学85.3%的学生和初中43.7%的学生出示了疫苗接种证明。至于风疹,我们确认幼儿园21.8%的学生、小学28.6%的学生和初中11.6%的学生出示了证明。结果,我们实现了麻疹目标,此前确定有感染或接种史的学生的接种率要超过90%。然而,我们没有实现风疹目标。这些系统比单纯的教育活动更有效,并且被认为通过持续实施可以提高疫苗接种的积极性。在易感染人群中,因过敏或癫痫发作而无法接种疫苗的比例总计为26%,但在一些学校超过40%。我们不仅应该教育家长,还应该教育医生关于疫苗接种的知识,并倡导进行疫苗接种。