Kanazawa Akishige, Kubo Shoji, Tanaka Hiromu, Takemura Shigekazu, Yamazaki Keiichi, Hirohashi Kazuhiro, Shiomi Susumu
Department of Gastroenterological and Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Japan.
Ann Nucl Med. 2003 Sep;17(6):507-9. doi: 10.1007/BF03006444.
Although it is recognized that hepatobiliary scan is of value in assessing postoperative complications of biliary surgery or cadaveric whole liver transplantation, there have been few reports regarding its usefulness following living donor liver transplantation. We performed living donor liver transplantation in a patient with biliary cirrhosis due to hepatolithiasis, using a right lobe graft from her sister. On the 15th postoperative day, bile discharge appeared from the operative wound. The leakage point could not be identified by computed tomography and cholangiography from the biliary drainage catheter. Hepatobiliary scan with Tc-99m Sn-N-pyridoxyl-5-methyltryptophan (99mTc-PMT) demonstrated biliary extravasation from the left side of the anastomosis of the hepatico-jejunostomy, indicating biliary leakage from the anastomosis. Conservative therapy was continued because the radioisotope flowed smoothly into the reconstructed jejunum and the biliary drainage catheter, and the leakage was stopped on the 63th postoperative day. Hepatobiliary scan is useful in determining the therapeutic plan as well as detection of bile leakage and identification of leakage points after living donor liver transplantation.
虽然人们认识到肝胆扫描在评估胆道手术或尸体全肝移植术后并发症方面具有价值,但关于其在活体肝移植后的应用报道却很少。我们为一名因肝内胆管结石导致胆汁性肝硬化的患者进行了活体肝移植,供肝为其姐姐的右叶肝脏。术后第15天,手术伤口出现胆汁引流。通过计算机断层扫描和经胆道引流导管的胆管造影均无法确定渗漏点。使用锝-99m N-吡哆醛-5-甲基色氨酸(99mTc-PMT)进行的肝胆扫描显示肝空肠吻合口左侧有胆汁外渗,提示吻合口存在胆漏。由于放射性同位素顺利流入重建的空肠和胆道引流导管,因此继续采取保守治疗,术后第63天胆漏停止。肝胆扫描对于确定活体肝移植后的治疗方案以及检测胆漏和确定渗漏点很有用。