Nöldeke H A, Friedrich J M, Wallner B, Weidenmaier W
Abteilung für Röntgendiagnostik der Radiologischen Klinik und Poliklinik, Universität Ulm.
Rofo. 1992 Dec;157(6):566-72. doi: 10.1055/s-2008-1033064.
For diagnosing a carotid artery stenosis, 26 patients underwent MR angiography. A spin echo (SE) sequence with presaturation on which the flowing blood appears with low signal intensity was applied, as well as a two- and three-dimensional gradient echo (GRE) sequence with flow compensation, showing blood flow with high signal intensity. Subsequently, projection angiograms were made from the MR images with a maximum intensity projection algorithm. Degree, length and localisation of a carotid artery stenosis were reviewed. To find out the clinical usability, the results of the MR angiograms were compared subsequently with the findings of intravenous digital subtraction angiography (i.v. DSA). In comparison with DSA a correlation in the degree of stenosis was noticed in 42 out of 48 SE-, in 39 out of 52 2-D GRE and in 41 out of 48 3-D GRE sequence angiograms. The length of 34 moderate and severe stenoses, demonstrated by DSA, was overestimated 5 times with the SE-sequence, 9 times with the 3-D and 23 times with the 2-D GRE sequence. MR angiography with a 3-D GRE sequence is suitable for screening for carotid artery stenosis. In cases of severe stenosis an SE sequence should be performed for more precise delineation of the stenotic lesion.
为诊断颈动脉狭窄，26例患者接受了磁共振血管造影检查。采用了一种预饱和自旋回波（SE）序列，在该序列上流动血液呈低信号强度，还采用了具有血流补偿的二维和三维梯度回波（GRE）序列，血流呈高信号强度。随后，利用最大强度投影算法从磁共振图像生成投影血管造影。对颈动脉狭窄的程度、长度和位置进行了评估。为了解其临床实用性，随后将磁共振血管造影的结果与静脉数字减影血管造影（i.v. DSA）的结果进行了比较。与DSA相比，48例SE序列血管造影中有42例、52例二维GRE序列血管造影中有39例、48例三维GRE序列血管造影中有41例在狭窄程度上存在相关性。DSA显示的34例中度和重度狭窄的长度，SE序列高估了5倍，三维序列高估了9倍，二维GRE序列高估了23倍。三维GRE序列磁共振血管造影适用于颈动脉狭窄的筛查。在严重狭窄的情况下，应进行SE序列检查以更精确地描绘狭窄病变。
