Vieira A, Hancock R, Limeback H, Schwartz M, Grynpas M
Faculty of Dentistry, University of Toronto, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, ON, Canada.
J Dent Res. 2003 Nov;82(11):909-13. doi: 10.1177/154405910308201112.
Despite fluoride's (F) well-documented ability to prevent caries, the effects of F concentrations on enamel and dentin apatite crystals are unknown. The present study examined the hypothesis that tooth F concentration and tooth crystallite size correlate. One hundred human unerupted third molars were studied-53 from Fortaleza-Brazil (F water 0.7 ppm), 23 from Toronto (1.0 ppm), and 24 from Montreal (0.2 ppm). F concentration was analyzed by Neutron Activation Analysis and apatite crystal size by powder x-ray diffraction. A positive correlation between dentin F concentration and enamel crystallite length and width was found. Enamel crystallite length was significantly greater in teeth from Fortaleza than in teeth from Toronto (p = 0.011) and Montreal (p = 0.003). Enamel crystallite widths were significantly greater in Fortaleza teeth compared with those from Toronto (p = 0.020) and Montreal (p < 0.001). No difference in the dentin crystallite size was seen in the 3 regions. Thus, tooth F concentration and crystallite size correlate.
尽管氟化物（F）预防龋齿的能力已有充分记录，但氟浓度对牙釉质和牙本质磷灰石晶体的影响尚不清楚。本研究检验了牙齿氟浓度与牙齿微晶尺寸相关的假设。研究了100颗人类未萌出的第三磨牙，其中53颗来自巴西福塔雷萨（氟含量0.7 ppm的水），23颗来自多伦多（1.0 ppm），24颗来自蒙特利尔（0.2 ppm）用中子活化分析法分析氟浓度，用粉末X射线衍射法分析磷灰石晶体尺寸。发现牙本质氟浓度与牙釉质微晶长度和宽度之间呈正相关。福塔雷萨牙齿的牙釉质微晶长度明显大于多伦多牙齿（p = 0.011）和蒙特利尔牙齿（p = 0.003）。与多伦多牙齿（p = 0.020）和蒙特利尔牙齿（p < 0.001）相比，福塔雷萨牙齿的牙釉质微晶宽度明显更大。在这三个地区，牙本质微晶尺寸没有差异。因此，牙齿氟浓度与微晶尺寸相关。
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