牙本质和牙釉质中的氟浓度是氟斑牙的良好指标吗？

Is fluoride concentration in dentin and enamel a good indicator of dental fluorosis?

作者信息

Vieira A P G F, Hancock R, Limeback H, Maia R, Grynpas M D

机构信息

Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1X5, Canada.

出版信息

J Dent Res. 2004 Jan;83(1):76-80. doi: 10.1177/154405910408300115.

DOI:10.1177/154405910408300115

PMID:14691118

Abstract

Despite some studies correlating dental fluorosis (DF) and fluoride (F) concentration in dental enamel, no information is available about DF and dentin F concentration. Our objective was to determine the correlation between teeth F concentration and DF severity in unerupted human 3rd molars, and the correlation between dentin and enamel F concentrations in the same tooth. Ninety-nine 3rd molars were studied-53 from Fortaleza, Brazil (F water, 0.7 ppm), 22 from Toronto (1.0 ppm), and 24 from Montreal (0.2 ppm). DF severity was evaluated according to the Thylstrup-Fejerskov Index, while F concentration was analyzed by Instrumental Neutron Activation Analysis. DF severity varied between TF0 and TF4, while F concentration ranged between 39 and 550 ppm in enamel and 101 and 860 ppm in dentin. Our results showed correlation between dentin F concentration and DF (r(S) = 0.316, p = 0.001), but no correlation between enamel F concentration and DF (r(S) = 0.154, p = 0.133). No correlation was observed between dentin and enamel F concentrations in the same tooth (r(S) = 0.064, p = 0.536).

摘要

尽管一些研究将牙釉质中的氟斑牙（DF）与氟化物（F）浓度联系起来，但关于DF与牙本质F浓度的信息却尚无定论。我们的目标是确定未萌出的人类第三磨牙中牙齿F浓度与DF严重程度之间的相关性，以及同一颗牙齿中牙本质和牙釉质F浓度之间的相关性。我们研究了99颗第三磨牙，其中53颗来自巴西福塔雷萨（F水，0.7 ppm），22颗来自多伦多（1.0 ppm），24颗来自蒙特利尔（0.2 ppm）。根据Thylstrup-Fejerskov指数评估DF严重程度，同时通过仪器中子活化分析来分析F浓度。DF严重程度在TF0至TF4之间变化，而牙釉质中的F浓度范围在39至550 ppm之间，牙本质中的F浓度范围在101至860 ppm之间。我们的结果显示牙本质F浓度与DF之间存在相关性（r(S)=0.316，p = 0.001），但牙釉质F浓度与DF之间无相关性（r(S)=0.154，p = 0.133）。在同一颗牙齿中，未观察到牙本质和牙釉质F浓度之间存在相关性（r(S)=0.064，p = 0.536）。