Moraca Robert J, Sheldon David G, Thirlby Richard C
Department of Surgery, Virginia Mason Medical Center, Seattle, Washington 98101, USA.
Ann Surg. 2003 Nov;238(5):663-73. doi: 10.1097/01.sla.0000094300.36689.ad.
To review the potential and proven benefits and complications of epidural anesthesia/analgesia.
Advances in analgesia/anesthesia have improved patient satisfaction and perioperative outcomes. Epidural anesthesia/analgesia is one of these advances that is gaining rapid acceptance due to a perceived reduction in morbidity and overall patient satisfaction.
A MEDLINE search was conducted for all pertinent articles on epidural anesthesia/analgesia.
Retrospective, prospective, and meta-analysis studies have demonstrated an improvement in surgical outcome through beneficial effects on perioperative pulmonary function, blunting the surgical stress response and improved analgesia. In particular, significant reduction in perioperative cardiac morbidity ( approximately 30%), pulmonary infections ( approximately 40%), pulmonary embolism ( approximately 50%), ileus ( approximately 2 days), acute renal failure ( approximately 30%), and blood loss ( approximately 30%) were noted in our review of the literature. Potential complications related to epidural anesthesia/analgesia range from transient paresthesias (<10%) to potentially devastating epidural hematomas (0.0006%).
Epidural anesthesia/analgesia has been demonstrated to improve postoperative outcome and attenuate the physiologic response to surgery.
回顾硬膜外麻醉/镇痛的潜在益处、已证实的益处及并发症。
镇痛/麻醉技术的进步提高了患者满意度和围手术期结局。硬膜外麻醉/镇痛是其中一项因被认为可降低发病率及提高患者总体满意度而迅速得到认可的技术。
对所有关于硬膜外麻醉/镇痛的相关文章进行了医学文献数据库(MEDLINE)检索。
回顾性、前瞻性及荟萃分析研究表明,硬膜外麻醉/镇痛通过对围手术期肺功能产生有益影响、减轻手术应激反应及改善镇痛效果,从而改善了手术结局。特别是,我们在文献回顾中注意到围手术期心脏发病率(约30%)、肺部感染(约40%)、肺栓塞(约50%)、肠梗阻(约2天)、急性肾衰竭(约30%)及失血(约30%)均有显著降低。与硬膜外麻醉/镇痛相关的潜在并发症范围从短暂感觉异常(<10%)到可能具有毁灭性的硬膜外血肿(0.0006%)。
硬膜外麻醉/镇痛已被证明可改善术后结局并减轻对手术的生理反应。