Konradsen Flemming, van der Hoek Wim, Cole Donald C, Hutchinson Gerard, Daisley Hubert, Singh Surjit, Eddleston Michael
Department of International Health, Institute of Public Health, University of Copenhagen, Panum, Blegdamsvej 3, 2200 Copenhagen, Denmark.
Toxicology. 2003 Nov 5;192(2-3):249-61. doi: 10.1016/s0300-483x(03)00339-1.
Hundreds of thousands of people are dying around the world each year from the effects of the use, or misuse, of pesticides. This paper reviews the different options to reduce availability of the most hazardous chemicals, focusing on issues in developing countries. Emphasis is placed on the fatal poisoning cases and hence the focus on self-harm cases. Overall, it is argued here that restricting access to the most hazardous pesticides would be of paramount importance to reduce the number of severe acute poisoning cases and case-fatalities and would provide greater opportunities for preventive programmes to act effectively. The aim should be to achieve an almost immediate phasing out of the WHO Classes I and II pesticides through national policies and enforcement. These short-term aims will have to be supported by medium- and long-term objectives focusing on the substitution of pesticides with safe and cost-effective alternatives, possibly guided by the establishment of a Minimum Pesticide List, and the development of future agricultural practices where pesticide usage is reduced to an absolute minimum. Underlying factors that make individuals at risk for self-harm include domestic problems, alcohol or drug addiction, emotional distress, depression, physical illness, social isolation or financial hardship. These should be addressed through preventive health programmes and community development efforts.
每年全球有数十万人死于农药使用或滥用的影响。本文回顾了减少最危险化学品可得性的不同选择,重点关注发展中国家的问题。重点放在致命中毒案例上,因此关注自残案例。总体而言,本文认为限制获取最危险的农药对于减少严重急性中毒病例数量和病例死亡率至关重要,并将为预防方案有效发挥作用提供更多机会。目标应该是通过国家政策和执法几乎立即逐步淘汰世界卫生组织第一类和第二类农药。这些短期目标将必须得到中长期目标的支持,中长期目标侧重于用安全且具有成本效益的替代品替代农药,这可能由制定一份《最低农药清单》来指导,并发展未来将农药使用降至绝对最低限度的农业做法。导致个人有自残风险的潜在因素包括家庭问题、酒精或药物成瘾、情绪困扰、抑郁、身体疾病、社会孤立或经济困难。这些问题应通过预防性健康方案和社区发展努力来解决。