Behera Ashish, Singla Neeraj, Sharma Nalin, Sharma Navneet
Post Graduate Institute of Medical Education & Research, Chandigarh, India.
J Family Med Prim Care. 2022 Jan;11(1):208-214. doi: 10.4103/jfmpc.jfmpc_916_21. Epub 2022 Jan 31.
To assess the pattern, prevalence and outcome of poisoning cases reporting to hospital in North India during COVID-19 pandemic.
An observational, prospective study was conducted for 100 patients reporting to medical emergency with history of poisoning intake from April 2020 to January 2021. Age range was 14-85 years. Obtained data were analysed using descriptive statistics and results were expressed as percentage and mean.
Out of 100 patients (77M, 33F), mean age of 32.6 years, most cases belong to age group of 20-30 years and 50% were matriculates and majority of the patients belonged to Punjab and Himachal Pradesh. The most common poisoning agents consumed were corrosives (34%) followed by Aluminium Phosphide (24%). Respiratory distress (53%), loss of consciousness (43%), acute kidney injury (36%) were the common clinical presentations. PSS (Poisoning Severity Score) was moderate in 52% of patients, severe in 14%, fatal in 16% and minor PSS in 18% of patients. 16 patients with fatal PSS and 16 patients with moderate to severe PSS got expired. High mortality of 33% was seen in our study.
The most vulnerable group in our study was of young males in age group of 21-30 years and less educated, who had lost their jobs due to COVID-19 pandemic lockdown. Corrosives were the most commonly consumed poison during lockdown. Our study found that scoring systems PSS and GCS were good assessment tools for degree of severity of poisoning at an early stage.
评估新冠疫情期间印度北部地区医院收治的中毒病例的模式、患病率及转归情况。
对2020年4月至2021年1月期间因中毒史前往医疗急救部门就诊的100例患者进行了一项观察性前瞻性研究。年龄范围为14至85岁。使用描述性统计方法对获得的数据进行分析，结果以百分比和均值表示。
100例患者中（男性77例，女性33例），平均年龄32.6岁，大多数病例属于20至30岁年龄组，50%为高中及以下学历，大多数患者来自旁遮普邦和喜马偕尔邦。最常摄入的中毒剂是腐蚀性物质（34%），其次是磷化铝（24%）。常见的临床表现为呼吸窘迫（53%）、意识丧失（43%）、急性肾损伤（36%）。52%的患者中毒严重程度评分（PSS）为中度，14%为重度，16%为致命，18%为轻度。16例致命PSS患者和16例中重度PSS患者死亡。本研究中观察到的死亡率高达33%。
本研究中最脆弱的群体是年龄在21至30岁、受教育程度较低的年轻男性，他们因新冠疫情封锁失去了工作。封锁期间最常摄入的毒物是腐蚀性物质。我们的研究发现，PSS和GCS评分系统是早期评估中毒严重程度的良好工具。
