[肉碱系列制剂在实验性四氧嘧啶糖尿病中的作用]
[The action of carnitine-series preparations in experimental alloxan diabetes mellitus].
作者信息
Kim E K, Trevisani C, Trevisani M
出版信息
Eksp Klin Farmakol. 1992 Jul-Aug;55(4):35-6.
PMID:1458184
Abstract
The study was undertaken to examine the effects of l-carnitine and acetyl-l-carnitine in rats and mice with experimental alloxan diabetes. The findings suggest that acetyl-l-carnitine is more effective against diabetes in increasing glucose tolerance, restoring the impaired response of glucagon to glucose, showing glycogen-sparing action than is l-carnitine.
摘要
本研究旨在考察左旋肉碱和乙酰左旋肉碱对实验性四氧嘧啶糖尿病大鼠和小鼠的影响。研究结果表明，在提高葡萄糖耐量、恢复胰高血糖素对葡萄糖的受损反应、显示糖原节省作用方面，乙酰左旋肉碱比左旋肉碱对糖尿病更有效。
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