在水溶液中具有高发射率的稳定镧系元素发光剂：Sm(3+)、Eu(3+)、Tb(3+)、Dy(3+)的多齿2-羟基间苯二甲酰胺配合物

Stable lanthanide luminescence agents highly emissive in aqueous solution: multidentate 2-hydroxyisophthalamide complexes of Sm(3+), Eu(3+), Tb(3+), Dy(3+).

作者信息

Petoud Stéphane, Cohen Seth M, Bünzli Jean-Claude G, Raymond Kenneth N

机构信息

Department of Chemistry, University of California, Berkeley, California 94720-1460, USA.

出版信息

J Am Chem Soc. 2003 Nov 5;125(44):13324-5. doi: 10.1021/ja0379363.

DOI:10.1021/ja0379363

PMID:14583005

Abstract

Efficient lanthanide (Ln) luminescent probes require good ligand-to-metal energy transfer and high aqueous stability. A family of ligands based on 2-hydroxyisophthalamide chelating units is reported. These form highly stable, eight-coordinate Ln complexes. Several of these (Ln = Sm, Eu, Tb, Dy) emit in the visible region with good ligand-to-lanthanide energy transfer. The absolute quantum yields of the two Tb complexes studies (Phi = 0.59, 0.61) and high absorbance make these the brightest luminescent probes for time-resolved detection; the emission spectrum of one complex can be seen down to 10-15 M. The low overlap of the four different Ln complexes enables their simultaneous detection and discrimination.

摘要

高效的镧系元素（Ln）发光探针需要良好的配体到金属的能量转移和高水稳定性。报道了一类基于2-羟基间苯二甲酰胺螯合单元的配体。这些配体形成高度稳定的八配位Ln配合物。其中几种（Ln = Sm、Eu、Tb、Dy）在可见光区域发射，具有良好的配体到镧系元素的能量转移。所研究的两种Tb配合物的绝对量子产率（Phi = 0.59、0.61）和高吸光度使它们成为时间分辨检测中最亮的发光探针；一种配合物的发射光谱在低至10-15 M时仍可见。四种不同Ln配合物的低重叠使得它们能够同时被检测和区分。