Loeb Mark
Department of Pathology, McMaster University, Hamilton, Ontario, Canada.
Clin Infect Dis. 2003 Nov 15;37(10):1335-9. doi: 10.1086/379076. Epub 2003 Oct 13.
Community-acquired pneumonia (CAP) is an important threat to the health of older adults. Streptococcus pneumonia remains the most important cause of CAP. Risk factors for CAP include alcoholism, asthma, immunosuppression, chronic respiratory or cardiac disease, institutionalization, and increasing age. Residents of long-term care facilities--a distinct subpopulation of elderly people--are at particularly high risk for developing pneumonia. In this setting, swallowing difficulties, witnessed aspiration, and receipt of sedatives are potentially modifiable risk factors. The clinical presentation in elderly patients is characterized by a reduced prevalence of nonrespiratory symptoms. Few randomized, controlled trials of therapy exist for elderly persons living in the community or in a long-term care setting. Good evidence exists to support the annual administration of influenza vaccine to older adults. Although evidence in clinical trials differs from evidence in observational studies that demonstrate clear benefits associated with the polysaccharide pneumococcal vaccine in this population, the vaccine is recommended for adults aged
社区获得性肺炎(CAP)是对老年人健康的一项重要威胁。肺炎链球菌仍然是CAP的最重要病因。CAP的危险因素包括酗酒、哮喘、免疫抑制、慢性呼吸道或心脏疾病、入住机构养老以及年龄增长。长期护理机构的居民——老年人中的一个独特亚群——发生肺炎的风险特别高。在这种情况下,吞咽困难、明确的误吸以及使用镇静剂是潜在的可改变危险因素。老年患者的临床表现特点是非呼吸道症状的发生率降低。针对社区或长期护理机构中的老年人,几乎没有随机对照治疗试验。有充分证据支持对老年人每年接种流感疫苗。尽管临床试验证据与观察性研究证据不同,后者表明多糖肺炎球菌疫苗对该人群有明显益处,但仍建议为年龄在……的成年人接种该疫苗