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组织学确诊为感染性肺炎的猫的临床病理、影像学特征及病因:39例(1991 - 2000年)

Clinicopathologic and radiographic features and etiologic agents in cats with histologically confirmed infectious pneumonia: 39 cases (1991-2000).

作者信息

Macdonald Ellen S, Norris Carol R, Berghaus Roy B, Griffey Stephen M

机构信息

Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616-8734, USA.

出版信息

J Am Vet Med Assoc. 2003 Oct 15;223(8):1142-50. doi: 10.2460/javma.2003.223.1142.

Abstract

OBJECTIVE

To determine clinicopathologic and radiographic features and etiologic agents in cats that died as a result of infectious pneumonia.

DESIGN

Retrospective study.

ANIMALS

39 cats.

PROCEDURE

Medical records of cats in which infectious pneumonia was confirmed by histologic examination of necropsy specimens were reviewed. Signalment, clinical signs, and results of a CBC, viral serologic tests, and thoracic radiography were evaluated. Infectious agents were classified as bacterial, viral, fungal, protozoal, or parasitic. Histologic features (severity, duration, anatomic location, and distribution) were analyzed.

RESULTS

Clinical signs referable to the respiratory tract were not detected in 14 of 39 (36%) cats, and results of a CBC (4/18 cats) and radiography (3/13) were unremarkable. Sixteen of 39 (41%) cats lacked clinical signs of systemic illness. Etiologic agents identified included bacteria (n = 21), viruses (11), fungi (6), protozoa (2), and parasites (1). Cats with clinical signs related to the respiratory tract (19/24 [79%] cats) were more likely to have severe histologic changes than cats without signs related to the respiratory system (6/14). Twenty-nine of 38 (76%) cats had histologic evidence of systemic disease, whereas the remaining cats had lesions limited to the respiratory tract.

CONCLUSIONS AND CLINICAL RELEVANCE

Infectious pneumonia is uncommon in cats. Cats with infectious pneumonia may lack clinical signs and have unremarkable results for a CBC and thoracic radiography, yet frequently have systemic infections. Therefore, clinicians should maintain an index of suspicion for pneumonia and evaluate the respiratory tract when infection is detected in other organ systems.

摘要

目的

确定因感染性肺炎死亡的猫的临床病理特征、影像学特征及病因。

设计

回顾性研究。

动物

39只猫。

方法

对经尸检标本组织学检查确诊为感染性肺炎的猫的病历进行回顾。评估其特征、临床症状以及血常规、病毒血清学检测和胸部X光检查结果。将感染源分为细菌、病毒、真菌、原生动物或寄生虫。分析组织学特征(严重程度、病程、解剖位置和分布)。

结果

39只猫中有14只(36%)未检测到呼吸道相关临床症状,18只猫中的4只血常规检查结果及13只猫中的3只X光检查结果无异常。39只猫中有16只(41%)缺乏全身疾病的临床症状。确定的病因包括细菌(n = 21)、病毒(11)、真菌(6)、原生动物(2)和寄生虫(1)。有呼吸道相关临床症状的猫(19/24 [79%])比无呼吸道相关症状的猫(6/14)更易出现严重组织学改变。38只猫中有29只(76%)有全身疾病的组织学证据,其余猫的病变局限于呼吸道。

结论及临床意义

感染性肺炎在猫中并不常见。患有感染性肺炎的猫可能没有临床症状,血常规和胸部X光检查结果无异常,但常伴有全身感染。因此,临床医生在检测到其他器官系统感染时,应保持对肺炎的怀疑指数并评估呼吸道情况。

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