Baty Vincent, Michalet Véronique, Tanière Philippe, Chalabreysse Philippe, Magnin Bernard, Ray-Coquard Isabelle
Clinique Mutualiste Eugène André, 107 rue Trarieux, 69424 Lyon.
Gastroenterol Clin Biol. 2003 Aug-Sep;27(8-9):828-32.
Most cases of liver failure related to the infiltration of the liver by neoplastic cells are associated with hematological neoplasia or small cell carcinoma of the lung. We report case of liver failure related to a rare infiltration of the liver by a micropapillary bladder carcinoma. Micropapillary bladder cell carcinomas have recently been isolated among bladder tumors. They are characterized by life-threatening features as they spread rapidly to the interstitial stromal matrix leading to a highly aggressive course. The present case emphasizes the pathological features and poor prognosis of these neoplasia, as rapid submucosal spreading may prevent curative locoregional treatment.
大多数与肿瘤细胞浸润肝脏相关的肝衰竭病例与血液系统肿瘤或肺小细胞癌有关。我们报告了一例与微乳头型膀胱癌罕见的肝脏浸润相关的肝衰竭病例。微乳头型膀胱细胞癌最近在膀胱肿瘤中被分离出来。它们的特点是具有危及生命的特征,因为它们会迅速扩散到间质基质,导致病程高度侵袭性。本病例强调了这些肿瘤的病理特征和预后不良,因为快速的黏膜下扩散可能会妨碍根治性局部治疗。